Liposome Customization Services

CD Formulation has been dedicated to liposome development for many years, and our rich experience has made us experts in liposome preparation and manufacturing. Our goal with our liposome customization service is to provide you with high-quality, customer-satisfying liposome products. We are constantly adding to our extensive research list of liposome products. With years of experience in comprehensive lipid synthesis, our team can solve most liposome customization problems. If you are unable to find the appropriate liposome product to ensure the success of the project or you have suggestions for new products needed in the field, our team is ready to take on a new challenge.

Fig.1 Schematic diagram of the mechanism of drug molecules passing through the corneal barrier after local administration. (Kashif Muhammad, et al., 2018)

Advantages of Our Custom Liposomes

• High biocompatibility and degradability. Liposomes exhibit high biocompatibility and degradability due to their structural similarity to cell membranes, which is attributed to the composition of the phospholipid bilayer. With years of research on phospholipids and liposomes, we also can offer customized lipid synthesis and formulation development, ensuring the production of highly biocompatible and degradable liposomes.
• Site-targeting. Through physical or chemical means, we can modify the structure of the surface of the liposome to make it tissue-targeting, prolong the effective retention time of the liposome at the lesion site, and even achieve efficient targeted drug delivery.
• Delivery flexibility. Our customized liposomes have been used as effective carriers for diverse substances, including drugs, toxins, proteins (peptides), enzymes, antigens (antibodies), nucleic acids, enzymes, dyes, chemical raw materials, fluorescent reagents, etc.
• An extensive array of applications. Our custom liposomes, serve as a versatile delivery system can not only for therapeutic purposes but also for imaging, enzyme reactions, chemical reactions, and more.

Our Services for Liposome Customization

Custom Long-circulating Liposome Service

• Our long-circulating liposomes not only increase drug retention in the blood but also enhance drug accumulation at tissue sites.
• This service addresses issues such as the solubility of hydrophobic drugs, low encapsulation rates, and prolonged in vivo half-lives.

Custom Proliposome Service

• Our technique enhances the solubility and bioavailability of certain insoluble substances.
• Proliposomes primarily exist in a flexible state, typically as dry powder, which maintains stability during encapsulation in unit doses and the sterilization process.
• Suitable for industrial production

Custom Polymer-modified Liposome Service

• We are capable of synthesizing various polymers and performing complete surface modifications on liposomes, such as polyamino acids, chitosan copolymers, dendrimers, and more.
• We offer a polymer database to help select suitable polymers.
• Our technique enhances the lysosome escape effect.

Custom Environmentally Responsive Liposome Service

• Environmentally responsive liposome (such as pH, temperature, light, magnetica, ultrasound, and enzyme, redox stimuli)
• We combine multiple response stimulation technologies to control and sustain the drug release, improving liposome targeting and bioavailability.

Custom Immunoliposome Service

• This service enables screening across multiple colonies and includes the use of full-length antibodies, antibody fragments, and aptamers.
• Immunoliposomes serve as carriers for a broad spectrum of ingredients, encompassing tumor therapy drugs, genes, and applications in live imaging and biosensor fields.

Custom Glucose Modified Liposome (GML) Service

• A viable targeting system for cancer therapy.
• Glucose-functionalized liposomes show a significant tumor tissue accumulation preference.

Custom Flexible Liposome Service

• Applications include cosmetics and transdermal preparations (carriers of antimicrobial drugs, non-steroidal anti-inflammatory drugs, wound healing drugs, gene transfection carriers, tumor drugs carriers).
• Beyond traditional benefits, their specific advantages include enhanced absorption, improved moisture permeability, and effective barrier repair functions.

Custom GSH-liposome Service

• We offer customization services for GSH-liposomes tailored to research-specific requirements.
• Customization is available for oral supplementation to meet individual needs and preferences.
• We provide customization of cosmetic glutathione liposomes to enhance the effectiveness and application in skincare products.

Custom Reactive Oxygen Species (ROS)-responsive Liposome Service

• ROS-responsive liposome customization
• Multiple stimuli responsive liposome customization
• ROS-responsive liposome hydrogel customization
• The study of ROS responsiveness and drug release rate
• Analysis of physicochemical properties

Custom Fusogenic Liposome Service

• The platform facilitates the innovative fusogenic liposome products and supports fusion mechanism study, offering more cutting-edge concepts.
• Fusogenic liposomes has emerged as a promising method for intracellular fluorescent probes.

Custom Multivesicular Liposome Service

• At our platform, it can be loaded with a variety of active substances.
• High doses and high stability can be achieved.
• Applications are extensive, covering food, cosmetics, and medical domains.

Custom Hollow Fiber Liposome Service

• The technique uses a membrane contactor in a hollow fiber configuration.
• The technique is simple and rapid and has the potential to continuously produce liposome suspensions on a large scale.

Custom Labeled Liposome Service

• Labeled liposomes can be employed for visualize tumors, thereby advancing the development of biomarkers and imaging agents.
• The application predominantly focuses on flow cytometry and in vivo imaging.

Why Partner with Us?

• Advanced development platform. Our team leverages a cutting-edge development platform, featuring an array of state-of-the-art equipment and instruments tailored for producing sophisticated liposomes with diverse functionalities.
• Flexible customization. We can design and synthesize liposomes with tailored functions and properties to meet customer-specific needs, including drug delivery objectives, functionality, and size specifications.
• Skilled teams. Our skilled team comprises seasoned experts and scientists with multidisciplinary expertise, adept in evaluating liposomes and designing in vitro and in vivo experiments, encompassing validation of targeting, controlled release, biocompatibility, and therapeutic efficacy.
• High-quality. We ensure high-quality standards, with liposome properties rigorously assessed and controlled through particle size analysis, zeta potential measurements, transmission electron microscopy, and additional analytical methods.

As a global leader in nanotechnology development, CD Formulation has been dedicated to liposome development for many years. If you need any help, please do not hesitate to contact us.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.