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Custom Specialty Peptides Synthesis

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"Specialty peptides" refer to a class of peptides that have distinct properties and applications, often characterized by their specific sequences, structures, and biological activities. With decades of hands-on experience in the field of peptide synthesis and research, CD Formulation has developed specific skills and expertise that enable it to produce specialty peptides of exceptional quality. We have become experts in designing and producing specialty peptides of the highest quality, even for complex or unusual peptide sequences. Our highly qualified and dedicated expert team ensures that the most appropriate methods and technologies are selected for each specialty peptide project.

What is Specialty Peptides?

Specialty peptides are short chains of amino acids, typically consisting of 2 to 50 amino acids, that have unique properties or functions not found in standard peptides. They are often synthesized or modified for specific applications in various fields, including biochemistry, pharmaceuticals, and biotechnology.

Fig. 1 Specialty peptides. Fig. 1 Specialty peptide types. (CD Formulation)

Explore Our Custom Specialty Peptides Synthesis Services

At CD Formulation, our team of scientists has the expertise and specific skills to design and synthesize a range of specialty peptides for a variety of applications. We have a large portfolio of synthetic strategies, allowing us to select the most appropriate technology to support each individual peptide project.

Our reliable services have supported clients around the world for many years, allowing us to synthesize even the most unusual and complex peptides with outstanding quality.

Our specialty peptide services include, but are not limited to:

Specialty Peptides
Multiple Antigenic Peptide (MAP)	Cyclic Peptide	Stapled Peptide
Long Peptide	Cell Penetrating Peptide (CPP)	Linear Peptide
Peptoid	Disulfide-Rich Peptide (DSR)	Peptide Antigen
D-Amino Acid-Containing Peptide	Bicyclic Peptide	Carrier Protein-Conjugated Peptide
Enzyme Labeled Peptide	Isotope Labeled Peptide	Quenched Fluorescent Peptide (FRET Peptide)
Fluorescence Labeled Peptide	Imaging Agent Labeled Peptide

Our Specialty Peptide Synthesis Capabilities

With rich experience and expertise in peptide synthesis and research, CD Formulation has established a first-class peptide synthesis platform that can provide high-quality customized special peptides in a short time. We have mature peptide synthesis and purification methods, especially solid phase peptide synthesis (SPPS), liquid phase peptide synthesis (LPPS), and biosynthesis, to provide high-quality special peptides.

Comprehensive peptide synthesis strategy.
Customized special peptides on demand.
First-class synthesis equipment.
Independent peptide production (synthesis & purification) platform.

Peptide Manufacturing & Analytical Services

In addition to peptide synthesis capabilities, CD Formulation combines flexible GMP manufacturing facilities with cutting-edge peptide analytical knowledge to provide a full range of quality control testing services to accelerate the commercialization of your products, including:

Peptide identification (ESI-MS).
Peptide Molecular weight determination.
Peptide sequencing.
Peptide quantification/peptide content determination.
Peptide purity and impurity analysis (HPLC/UV).
Amino acid sequence.
Amino acid composition determination.
Net peptide content.

Enantiomeric purity testing (GC/MS; LC).
Residual counterion testing (e.g. TFA).
Elemental analysis.
Residual solvent testing.
Water content testing (GC or KF).
Peptide solubility testing.
Peptide stability testing.

Optical rotation determination.
Bioburden testing(TAMC/TYMC).
Bacterial endotoxin testing.
Sterility testing.
Cytotoxicity testing.
Process/product related impurity testing.
Other pharmacopoeia testing.

Why Choose Us for Custom Specialty Peptides Synthesis?

We have assembled a dedicated team of peptide experts with extensive experience in peptide synthesis, modification, characterization, and purification.
We have a first-class peptide synthesis platform equipped with advanced technologies and equipment, including SPPS, LPPS, microwave SPPS, and chemo-enzymatic peptide synthesis (CEPS), allowing us to handle any possible complex challenges.
We provide scalable solutions, from small-scale production for research to large-scale manufacturing for clinical and commercial applications.
Our rigorous quality assurance protocols ensure that each peptide product meets industry standards and regulatory requirements. We implement comprehensive testing at every stage of synthesis to guarantee efficacy and safety.
Fast Turnaround Time: With streamlined processes and efficient project management, we provide a fast timeline for specialty peptide synthesis, allowing you to quickly move from research to clinical trials.

Publication

Published Data

Technology: Synthesis of Cyclic Peptides

Journal: Molecules.

IF: 4.2

Published: 2022

Results:

The authors describe a method for synthesizing a series of cyclic peptides in SPPS based on structural modification of the photolabile protecting group of 2-(o-nitrophenyl)propan-1-ol (Npp-OH) and verifying it. The results show that 3-(o-nitrophenyl)butan-2-ol (Npb-OH) has a high photorelease rate, is highly tolerant to the key conditions of Fmoc-SPPS (20% piperidine DMF alkaline solution, and pure TFA acidic solution), and can be used as a carboxyl protecting group in aliphatic and aromatic carboxyl groups. It was confirmed that Npb-OH can be successfully used in the synthesis of head-tail cyclic peptides and side-chain-tail cyclic peptides.

Fig. 2 The synthesis of cyclic peptide. Fig. 2 The synthesis of head-to-tail cyclic peptide I and head-to-side peptides II and III based on the Npb strategy. (Chen T, et al., 2022)

CD Formulation's specialty peptide synthesis services are tailored to meet the specific needs of researchers and organizations seeking high-quality peptides for drug discovery, vaccine development, diagnostics, and other scientific endeavors. Please don't hesitate to contact us if you are interested in our services. We look forward to cooperating with you.

References

Chen T, Wang G, Tang L, et al. Synthesis of Cyclic Peptides in SPPS with Npb-OH Photolabile Protecting Group. Molecules. 2022; 27(7):2231.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.

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