Custom Modified Peptide Synthesis

Peptide modification is an important way to change the main chain structure or side chain groups, effectively improving its stability, biocompatibility, selectivity, and drug release characteristics. CD Formulation is one of the global leaders in peptide modification. Our extensive synthesis capabilities and rich experience enable us to provide various peptide modification services, including C-terminal modification, N-terminal modification, PEGylation, post-translational modification, fluorescent labeling, and biotinylation.

What is Peptide Modification?

Peptide modification refers to chemical changes to peptides (short chains of amino acids) to enhance their properties, stability, or function. Depending on the final intended use, these modifications can be N-terminal modifications, C-terminal modifications, uncommon and unnatural amino acids, biotinylation, cyclization, peptide PEGylation, phosphorylation, prenylation, linkers and spacers, fluorescently labeled peptides, etc. Peptide modification has important application value in biomedicine and drug development. By chemically changing the peptide, its properties and functions can be improved.

• Research: Peptide modifications help study protein interactions and complexes. This is mainly through their ability to stabilize the peptide or protein complex they bind to.
• Pharmaceutical: Peptide modifications help improve the bioavailability, targeting, and stability of drugs. For example, C-terminal modifications (such as N-alkylamides) make peptides more easily penetrate membranes, and unnatural amino acids can be used in antibody-drug conjugates.

Fig. 1 Types of peptide modifications. (CD Formulation)

Explore Our Custom Modified Peptide Synthesis Services

As an expert in peptide modification, CD Formulation focuses on the synthesis of various post-translationally modified (PTM) peptides. Our reliable synthesis procedures and excellent peptide analysis technology allow us to solve any possible challenges in the development and production of peptide therapeutics.

Importantly, we can flexibly adapt the best synthesis method during peptide synthesis to ensure the efficiency, safety, and stability of the product, which depends on the complexity of your project. Our goal is to provide customers with high-quality modified peptide products to accelerate their drug development process and promote the realization of new therapies.

The following are high-quality modified peptide options that CD Formulation can provide:

Peptide Manufacturing & Analytical Services

In addition to peptide synthesis capabilities, we combine flexible GMP manufacturing facilities with cutting-edge peptide analytical knowledge to provide a full range of quality control testing services to accelerate the commercialization of your products, including

Why Choose Us for Custom Modified Peptide Synthesis?

• We have a team with rich experience and strong expertise in peptide modification, who have completed hundreds of peptide modification projects.
• We provide a wide range of peptide post-translational modifications, including phosphorylation, acetylation, prenylation, glycosylation, etc.
• We provide modified peptides with a success rate close to 100%.
• High-throughput synthesis, ideal for vaccine generation, new antigen peptides, and epitope mapping.
• We provide flexible product expansion, from nanomoles, milligrams, and grams to kilograms.
• We provide scalable solutions, from small-scale production for research to large-scale manufacturing for clinical and commercial applications.
• We provide a fast timeline for modified peptide synthesis, allowing you to quickly move from research to clinical trials.

Publication

CD Formulation has extensive experience in custom peptide modification and synthesis. Each synthesis step is subject to our strict quality control. Please don't hesitate to contact us if you would like to learn more about the possibilities of your peptide modification. We look forward to cooperating with you.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.