As a drug carrier, oral thin films have attracted increasing attention in the field of drug delivery due to their ability to safely load medications and release them in a controlled manner, which improves drug efficacy. They are more consistent with patient compliance and alternative to oral drug delivery employing self-application, prolonged action, and quick termination if drug toxicity is produced. CD Formulation provides professional development and characterization services for oral film drug delivery systems.

Application of Oral Thin Film in Medical Areas

With a wide range of suitable drug compounds that are capable of being loaded into oral thin films, the therapeutic application of oral thin films rapidly increased, with more and more potential patient groups benefiting from using oral thin films as the delivery platform in recent years, including cardiovascular diseases, pain disorders, oral inflammation, nausea and vomiting, mood or mental disorders, respiratory system, erectile dysfunction and pulmonary diseases, etc.

Fig.1 Therapeutic applications of orodispersible films (ODFs) delivered. (Yu Tian, et al., 2023)

Examples of Commercially Available Oral Thin Films

Some oral thin film products are becoming commercially available for treating sore throats, relieving pain in the mouth and gums, schizophrenia, etc.

Oral Thin Films for Therapeutic Research

CD Formulation can help customers develop oral thin films suitable for a variety of potential patients. Oral thin films can be formulated and designed to obtain either local or systemic absorption, including:

Oral Thin Film for Cardiovascular Therapeutic Research

Some of these drugs may suffer from extensive first-pass metabolism after oral administration, thus leading to low bioavailability. Studies have found that incorporating cardiovascular drugs into oral thin films can significantly avoid the acceptance effect and greatly improve patient compliance, especially for hypertensive patients after stroke.

Oral Thin Film for Pain Relief Research

As the fast onset of action of drugs is highly required for treating pain disorders, the combination of analgesia with oral thin films can provide more rapid relief for acute pain.

Oral Thin Film for Mood or Mental Disorder Therapy Research

Mood and mental disorders include depression, anxiety, bipolar disorder, neuroses, psychoses, and schizophrenia. As the administration of oral thin films doesn't need any water and can be easily applied, oral thin films are more suitable for treating these disorders.

Oral Thin Film for Respiratory Disease Therapy Research

The primary treatment for respiratory system diseases now is injection. However, long-term drug administration, low patient compliance, high doses, and frequent dosing intervals all contribute to the rising risk of drug resistance. Using oral thin film as a carrier has become an ideal dosage for treating respiratory diseases.

Antihistamines Oral Thin Film Formulation Research

Oral thin films for antihistamines are a relatively new and innovative way to deliver allergy relief and manage symptoms of histamine-related conditions.

Oral Thin Film for Erectile Dysfunction Therapy Research

Oral thin film technology for the delivery of erectile dysfunction medications has become a potential alternative to traditional oral pills, which has the advantages of rapid onset, accurate dosing, ease of administration, discreetness and convenience.

Custom Oral Thin Film Development

Our team of experts delivers a full range of services, from initial concept development to commercialization, to support the development of innovative and effective oral thin film drug products.

Published Data

CD Formulation has extensive experience in developing and producing oral thin films, and we are equipped with a wide range of high-performance industrial equipment for the contract production of oral thin films. If you require our oral thin film for medical areas services, please contact us by phone or email, and our colleagues will get back to you within three working days.