Oral Thin Film for Erectile Dysfunction Therapy Research

Oral thin film disintegrates rapidly in the oral cavity, usually within a few minutes, without drinking or chewing, thus providing a valuable alternative to the marketed solid oral forms (tablets) in erectile dysfunction. Leveraging our advanced oral thin film technology platform and extensive drug design expertise, CD Formulation provides tailored R&D services for erectile dysfunction oral thin films. Our customized solutions are designed to meet the unique needs of researchers, supporting innovation and paving the way for potential commercialization.

Advantages of Oral Thin Film for Erectile Dysfunction

• Offer fast, accurate dosing in a safe, efficacious format
• Convenient and portable
• Without the need for water or measuring devices
• Fewer side effects

Main Applications of Oral Thin Film for Erectile Dysfunction

Applications	Detailed Information
Case 1: Active Ingredients: Tadalafil	Tadalafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is clinically used for erectile dysfunction by oral administration. The results show that the oral thin films formulated with micronized Tadalafil may be an alternative to commercial tablets for male erectile dysfunction. Fig.1 Formulation and characterization of tadalafil-loaded orodispersible films. (Zong-Liang Zhao, et al., 2023)
Case 2: Active Ingredients: Sildenafil	Sildenafil oral film is the first oral thin film in Europe for erectile dysfunction and can be used interchangeably with the conventional film-coated formulation to address better the needs and expectations of men with erectile dysfunction.
Case 3: Active Ingredients: Sildenafil citrate	The extensive first-pass metabolism and poor aqueous solubility of sildenafil citrate contribute to the poor oral bioavailability, so the fast disintegration oral thin films are more suitable to be the delivery platform for sildenafil citrate with its ease of administration and carrying.

Our Oral Thin Film Technology Platform

Taste-Masking and Flavor Optimization Platform

APIs used for erectile dysfunction often have a bitter taste, and the oral thin film comes into direct contact with the mouth, releasing the APIs, and the bad taste will reduce the people's compliance. We have built a taste-masking and flavour optimization technology platform to assist in selecting suitable flavours that align with people's preferences.

Oral Thin Film Manufacturing Platform

We provide customers with CGMP manufacturing platforms from laboratory to commercial scale, including pilot scale-up manufacturing, preclinical manufacturing, and commercial manufacturing.

Fig.2 Industrial manufacturing process of oral thin film. (Irma E. Cupone, et al., 2022)

Quality Control Platform

Our manufacturing platform incorporates stringent quality control measures to ensure that each batch of oral thin films meets regulatory standards and internal quality specifications, including in-process testing, real-time monitoring, and comprehensive analytical capabilities.

Custom Oral Thin Film Development Services

Our team is dedicated to tailoring oral thin film formulation research that ensures accurate dosing, rapid absorption, pleasant taste, and optimized bioavailability of APIs, addressing the specific requirements of erectile dysfunction.

Why Choose CD Formulation?

• Our carefully customized and properly quality-tested provide safety, effectiveness, and convenience.
• Leverage our advanced taste-masking technology and multi-layer oral thin film development technology platform to improve the taste of API and thus enhance people's compliance.
• We can provide oral thin film formulation research services to meet the specific needs of people with erectile dysfunction.

With our cutting-edge technology and deep expertise, CD Formulation empowers global researchers to advance oral thin film research for erectile dysfunction to new heights. For inquiries about our R&D services, please contact us via phone or email, and our team will respond within three business days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.