Tetracycline

Category

Anti-Infectives

Molecular Formula

C22H24N2O8

Appearance

yellow to yellow orange Powder

Grade

Pharmaceutical Grade

Standard

BP/EP/USP/CP/IP/JP

Description

Tetracycline is an antibiotic catalyzed by chloromycin dehalogenated biosynthesis, low toxicity, as early as 1948 began to be used in clinic

Chemical Name

12,12a-pentahydroxy-6-methyl-1,11-dioxo-1

CAS Number

60-54-8

Synonyms

12,12a-pentahydroxy-6-methyl-1,11-dioxo-1;4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide;4a,5Chemicalbook,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-4-(dimethylamino)-4;6-methyl-1,11-dioxy-2-naphthacenecarboxamide;abramycin;bio-tetra;bristaciclinalpha;bristacycline

Solubility

95% ethanol: soluble12.5mg/mL

Storage

2-8°C

Applications

1. Tetracycline is the first choice or drug of choice for the treatment of the following diseases: (1) Rickettsial diseases, including epidemic typhus, endemic typhus, Rocky mountain fever, tsutsugamushi disease, Rickettsial pneumonia and Q fever; (2) Mycoplasma infection such as mycoplasma pneumonia, urethritis caused by ureaplasma urealyticum, etc.; (3) Chlamydia infection, including chlamydia pneumoniae pneumonia, psittacosis, venereal lymphogranuloma and chlamydia trachomatis infection; (4) Recurrent fever caused by Chemicalbook spirochaeta; (5) Brucellosis (in combination with aminoglycosides); (6) Cholera; (7) tularemia caused by Bacillus tularemia; (8) Plague caused by Yersinia pestis. 2. Tetracycline can also be used for the treatment of tetanus, gas gangrene, yaws, syphilis, gonorrhea, non-gonococcal urethritis and leptospirosis allergic to penicillin antibiotics. 3. It can also be used for the treatment of acne with significant inflammatory response.

Boiling Point

554.44°C (rough estimate)

Melting Point

175-177 °C(lit.)

Density

1.3809 (rough estimate)

Product Description

Tetracycline is an antibiotic catalyzed by chloromycin dehalogenated biosynthesis, low toxicity, as early as 1948 began to be used in clinic

Molecular Weight (g/mol)

444.43