Sodium Oleate

Category

Cosmetic Surfactants

Molecular Formula

C18H33NaO2

CAS Number

143-19-1

Synonyms

Sodium oleate;oleic acid sodium salt;sodium cis-9-octadecanoate;eunatrol;Lunac SO 90L

Storage

-20ºC

Boiling Point

359.999ºC at 760 mmHg

Melting Point

232-235ºC(lit.)

Density

0.9 g/cm3

Product Description

Bretazenil (Ro16-6028) is an imidazopyrrolobenzodiazepine anxiolytic drug that is derived from the benzodiazepine family and was invented in 1988. It is most closely related in structure to the benzodiazepine antagonist flumazenil, although its effects are somewhat different. It is classed as a high-potency benzodiazepine due to its high-affinity binding to benzodiazepine binding sites where it acts as a partial agonist. Its profile as a partial agonist and preclinical trial data suggests that it may have a reduced adverse effect profile. In particular, bretazenil has been proposed to cause a less strong development of tolerance and withdrawal syndrome. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5, and α6 subunit-containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.

EC Number

205-591-0

Molecular Weight (g/mol)

304.443

Flash Point

270.099ºC

Physical State

Powder

MDL number

MFCD00004438

Stability

Stable. Incompatible with strong oxidizing agents.

Safety Statements

S22-S24/25

WGK Germany

1

RTECS

RK1200000

HS Code

2916150000

Color

White