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Sodium 2-Hydroxypropiomate Solution
Product Details
Category
Humectants; Stabilizers; pH adjuster; Wetting agents
Molecular Formula
C3H5NaO3
Molecular Weight
112.06
Grade
Pharmceutical Excipients
Description
Sodium lactate occurs as a clear, colorless, slightly syrupy liquid. It is odorless, or has a slight odor with a characteristic saline taste. It is hygroscopic.
UNII
TU7HW0W0QT
Chemical Name
Sodium lactate
CAS Number
72-17-3
Synonyms
E325; 2-hydroxypropanoic acid monosodium salt; Lacolin; lactic
acid monosodium salt; lactic acid sodium salt; natrii lactatis solutio;
Patlac; Purasal; Ritalac NAL; sodium a-hydroxypropionate.
acid monosodium salt; lactic acid sodium salt; natrii lactatis solutio;
Patlac; Purasal; Ritalac NAL; sodium a-hydroxypropionate.
Administration route
Infiltration; Intraperitoneal; Intravenous; Oral; Intracardiac; Intramuscular; Subcutaneous
Dosage Form
Epidural, IM, IV, and SC injections; oral
suspensions; topical gels and solutions
suspensions; topical gels and solutions
Stability and Storage Conditions
Sodium lactate should be stored in a well-closed container in a cool,dry, place. Sodium lactate is combustible and decomposes upon heating.
Commonly used amount and the maximum amount
The maximum dosage for intravenous injection: 50mg; the maximum dosage for general topical preparations: 51.3mg/g.
Source and Preparation
Add sodium hydroxide to lactic acid under cooling conditions to carry out neutralization reaction, then concentrate in vacuum at 50°C to remove 80% of water, and then neutralize with sodium hydroxide, crystallize or not crystallize.
Applications
Sodium lactate is widely used in cosmetics,food products and pharmaceutical applications including parenteral and topical formulations. Therapeutically, sodium lactate is used in infusions as a component of Ringer-lactate solution; as an alternative for sodium hydrogencarbonate in light acidosis; as a rehydrating agent; and as a carrier for electrolyte concentrates or medicines in perfusion/ infusion solutions.
Safety
This product is non-toxic and generally recognized as safe, and ADI has not made restrictive regulations. Patients with severe hepatic impairment who cannot convert lactate to bicarbonate should not use it.
Incompatibilities
This product has a compatibility reaction with novobiocin sodium, oxytetracycline hydrochloride, sodium bicarbonate, calcium sodium edetate, sulfadiazine, etc., and it is forbidden to be compatible with it.
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Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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