Norfloxacin

Category

Antibiotic

Molecular Formula

C16H18FN3O3

Appearance

Crystalline Powder

Grade

CEP/ISO

Standard

USP

Description

Norfloxacin and ofloxacin, levofloxacin, ciprofloxacin belong to the third generation fluoroquinolone antibacterial drugs, with a broad spectrum of antibacterial action, especially against aerobic gram-negative bacteria with high antibacterial activity, against the following bacteria in vitro has a good antibacterial effect: Most of the bacteria in the Enterobacteriaceae family, including E. coli, Enterobacter cloacae, Enterobacter aerogenes, E. coli, Klebsiella, Chemicalbook Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. Norfloxacin also has antibacterial activity against multi-drug resistant bacteria in vitro. The penicillin-resistant Neisseria gonorrhoeae, Haemophilus influenzae and Moraxella catarrh also have good antibacterial effects. Norfloxacin is A bactericide that causes bacterial death by inhibiting DNA synthesis and replication by acting on the A subunit of bacterial DNA helicase.

CAS Number

70458-96-7

Solubility

Very slightly soluble in water, slightly soluble in acetone and in ethanol (96 per cent).

Storage

Keep in dark place,Sealed in dry,Room Temperature

Applications

Clinically, it is used for infectious diseases of urinary tract, intestine, otolaryngology, gynecology, surgery and dermatology caused by sensitive bacteria.

Boiling Point

555.8±50.0 °C(Predicted)

Melting Point

220°C

Density

1.2504 (estimate)

Molecular Weight (g/mol)

319.33

Physical State

Crystalline Powder

Color

White to yellow