milrinone

Molecular Formula

C12H9N3O

Molecular Weight

211.224

Grade

Pharmaceutical grade

Description

Milrinone is a medication indicated for cardiac support in patients with acute heart failure, pulmonary hypertension, or chronic heart failure. It improves cardiac contractility (inotropy) and cardiac relaxation (lusitropy) and induces vasodilation.

Chemical Name

2-Methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile

CAS Number

78415-72-2

Applications

Milrinone is a commonly used therapy for severe pulmonary arterial hypertension (PAH),often in combination with other medications such as sildenafil.Targeting PDE3 with optimal doses and timing, milrinone prevents allergic inflammation in HDM-driven models of allergic airway inflammation.
It can be used in cardiopulmonary bypass cases, as it increases the flow in saphenous grafts and has a beneficiary effect in left ventricle function.