Methyl-β-cyclodextrin

Category

Cosmetic Chelating Chemicals

Molecular Formula

C54H94O35

CAS Number

128446-36-6

Solubility

H2O: 50 mg/mL

Quality Level

300

Storage

room temp

Melting Point

180-182 °C (lit.)

Product Description

Methyl-β-cyclodextrin is a heptasaccharide, soluble in water, and has more affinity to cholesterol due to the presence of hydrophobic core. Cyclodextrins are cyclic oligosaccharides consisting of 6, 7, or 8 glucopyranose units, usually referred to as α-, β-, or γ-cyclodextrins, respectively. These compounds have rigid doughnut-shaped structures making them natural complexing agents. The unique structures of these compounds owe their stability to intramolecular hydrogen bonding between the C2- and C3-hydroxyl groups of neighboring glucopyranose units. The molecule takes on the shape of a torus with the C2- and C3-hydroxyls located around the larger opening and the more reactive C6-hydroxyl aligned around the smaller opening. The arrangement of C6-hydroxyls opposite the hydrogen bonded C2- and C3-hydroxyls forces the oxygen bonds into close proximity within the cavity, leading to an electron rich, hydrophobic interior. The size of this hydrophobic cavity is a function of the number of glucopyranose units forming the cyclodextrin.

Molecular Weight (g/mol)

~1320

Flash Point

187 °C

Physical State

Powder

NACRES

NA.77

InChI Key

YZOUYRAONFXZSI-SBHWVFSVSA-N

Safety Statements

22-24/25

WGK Germany

3

HS Code

35051000

Water Solubility

Soluble in water

Color

White to off-white