Methoxy polyethylene glycol-poly(D, L-lactic acid)

Category

Carrier Excipients

Molecular Formula

CH3(C2H4))m(C6H10O2)n

Molecular Weight

PEG(2000; 3400; 5000); PLA(1000-60000)

Grade

Pharmceutical Excipients

Description

Custom

Chemical Name

Methoxy polyethylene glycol-poly(D, L-lactic acid)

Synonyms

MPEG-PLA

Stability and Storage Conditions

MPEG-PLGA is sensitive to light and temperature, for best use, the material should always be kept dry at low temperature and avoid frequent thawing and freezing. MPEG-PLGA should be kept dry at a low temperature below 4°C, protected from light, and the material can be handled under an inert gas for optimal stability. Retest the material after 12 months.

Applications

Methoxypolyethylene glycol-polylactic acid (mPEG-PLA) is a block copolymer, one end is a hydrophilic segment - methoxypolyethylene glycol, and the other end is an lipophilic segment - polylactic acid. By adjusting the molecular weight or the ratio of hydrophilic/lipophilic segments, methoxypolyethylene glycol-polylactic acid can be used as a carrier material for different types of drugs, and improve the water solubility, encapsulation efficiency and drug loading of drugs. Methoxypolyethylene glycol-polylactic acid can be made into drug-loaded microspheres, microcapsules, vesicles, and micelles to achieve sustained and controlled release of drugs, and can also be used as a tissue engineering scaffold with good hydrophilicity Material. Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and active compounds such as polyethylene glycol modified functional coatings.