Maltitol Solution

Category

Suspension aid; Sweetener

Grade

Pharmceutical Excipients

UNII

NA

Chemical Name

Maltitol solution

CAS Number

9053-46-7

Administration route

Oral

Dosage Form

Candies

Stability and Storage Conditions

Spitol solution can be stable for at least two years at room temperature and pH3~9. However, when stored at 50℃, pH2 for 3 months, there is 1.2% hydrolysis, and the color turns yellow. At pH3, the discoloration was not significant despite hydrolysis (0.2%) under the same storage conditions. At pH4~9, although under alkaline conditions, there is a slight yellowing, but not hydrolysis. Maltitol solutions should be supplemented with antibacterial preservatives, such as sodium benzoate or a mixture with hydroxybenzene. Maltitol solution is non-crystalline. Maltitol solution should be stored in an airtight container and kept in a cool, dry place.

Source and Preparation

Maltitol is produced by hydrogenation of high concentration maltitol liquid resulting from amylysis. The resulting maltitol solution contains hydrogenated homologues of oligosaccharides in the raw sugar solution.

Applications

Maltitol solution can be used alone or in combination with other excipients such as sorbitol as a sweetener in the prescription of oral pharmaceutical preparations. At the same time, it can also be used as a suspending agent in oral suspensions as a substitute for sucrose syrup because it has a certain consistency, is non-cariogenic, and has a lower caloric value. Maltitol solution is non-crystalline, which can prevent the sticking of crystals on the top of the bottle mouth of syrup and elixir. Maltitol solutions are also used in the preparation of lozenges, and in addition, they are used in the confectionary and food industries.