Product Details
Category
Coating material; Diluent; Granulating Agents; Suspension aid; Sweetener; Viscosifier
Molecular Formula
C12H24O11
Grade
Pharmceutical Excipients
Chemical Name
4-O-α-D-Glucopyranosyl-D-glucitol
Administration route
Oral
Dosage Form
Oral preparations
Stability and Storage Conditions
Maltitol has good temperature and chemical stability. Degradation occurs when heated above 200℃ (depending on time, temperature, and other major conditions). Maltitol reacts with amino acids to turn brown. Only when the relative humidity is 89% or higher at 20℃.
Source and Preparation
Maltitol is prepared from hydrogenated malt syrup. The starch is hydrolyzed to produce a high concentration of maltose, which is then hydrogenated with a catalyst. After purification and concentration, the syrup is crystallized.
Applications
Maltitol is widely used in oral preparations in the pharmaceutical industry. It is non-carious substance. Similar in sweetness to sucrose, it can be used as a diluent in oral dosage form and also in wet granulating and coating materials.