Product Details
Category
Dietary supplement; Emulsifying Agents; Skin Penetrant
Molecular Formula
C18H32O2
Grade
Pharmceutical Excipients
Chemical Name
(Z, Z)-9, 12-Octadecadienoic acid
Synonyms
Emersol 310; Emersol 315; leinoleic acid; 9-cis, 12-cis-linoleic acid; 9, 12-linoleic acid; linolic acid; cis, cis-9, 12-octadecadienoic acid; Pamolyn; Polylin No 515; telfairic acid
Stability and Storage Conditions
Linoleic acid is sensitive to air, light, moisture, and heat. It should be stored in a tightly sealed container under an inert atmosphere and refrigerated.
Source and Preparation
Linoleic acid is obtained by extraction from various vegetable oils such as safflower oil.
Applications
Linoleic acid is used in topical transdermal formulations, in oral formulations as an absorption enhancer, and in topical cosmetic formulations as an emulsifying agent, and in aqueous microemulsions. It is also used in parenteral emulsions for total parenteral nutrition and in nonprescription oral dietary supplements.
Safety
Linoleic acid is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as a nontoxic material. On exposure to the eyes, skin, and mucous membranes, linoleic acid can cause mild irritation.
Incompatibilities
Linoleic acid is incompatible with bases, strong oxidizing agents, and reducing agents.