Lactitol

Category

Sweetening agent

Grade

Pharmceutical Excipients

UNII

NA

Chemical Name

4-O-(β-D-Galactopyranosyl)-D-glucitol; 4-O-(β-D-Galactopyranosyl)-D-glucitol monohydrate; 4-O-(β-D-Galactopyranosyl)-D-glucitol dihydrate

CAS Number

585-86-4

Dosage Form

Monohydrate is moisture-free and stable under humid conditions. It is thermally stable and does not participate in the Maillard reaction. Under acidic conditions, lactiol hydrolyzes slowly to form sorbitol and galactose. Lactiol has strong resistance to microbial decomposition. Store in an airtight container. The storage period is more than 3 years when it is stored in a sealed container at 25℃ with 60% relative humidity.

Source and Preparation

It can be made by catalytic hydrogenation of lactose.

Applications

Lactiol is a caloric alternative to table sugar. It is also used as a thinner in solid preparations. Excipients are available on the market in direct tablet form, which is a mixture of lactose and lactiol. Can be used as a treatment of liver jaundice drugs, also used as laxative.