Product Details
Category
Cosmetic Color Additives
Molecular Formula
C5H5N5O
Synonyms
2-Amino-1,7-dihydro-6H-purin-6-one, 2-Amino-6-hydroxypurine, 2-Aminohypoxanthine
Solubility
hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green
Application
Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers.
Boiling Point
273.11°C (rough estimate)
Melting Point
>300 °C (lit.)
Density
1.4456 g/mL(rough estimate)
Product Description
Adenine, cytosine, thymine and guanine are the four main nucleobases found in nucleic acids DNA and RNA. Guanine is a purine derivative. It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine.
Molecular Weight (g/mol)
151.13
Refractive Index
2.0000 (estimate)
InChI Key
UYTPUPDQBNUYGX-UHFFFAOYSA-N
SMILES
NC1=Nc2[nH]cnc2C(=O)N1
InChI
1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
Stability
Stable. Incompatible with strong oxidizing agents.
Safety Statements
26-36-37/39
Water Solubility
practically insoluble