Product Details
Category
Bioadhesive Material; Emollient; Emulsifier; Emulsion Stabilizer; Gelling Agents; Nonionic Surfactant; Continuous Release Agents
Molecular Formula
C21H40O4
Grade
Pharmceutical Excipients
Chemical Name
9-Octadecenoic acid (Z), monoester with 1, 2, 3-propanetriol
Synonyms
Glycerol Mono-oleate(BP); Aldo MO; Atlas G-695; Capmul GMO; glycerol-1-oleate; glyceroli mono-oleas; glyceryl mono-oleate; HallStar GMO; Imwitor 948; Kessco GMO; Ligalub; monolein; Monomuls 90-O18; mono-olein; a-mono-olein glycerol; Peceol; Priolube 1408; Stepan GMO; Tegin
Administration route
Oral; Topical
Stability and Storage Conditions
Monoolein should be stored in an airtight container in a cool, dry place away from light.
Commonly used amount and the maximum amount
When used as emulsifier or cosolvent in topical preparations, the maximum dosage is generally 5mg/g.
Source and Preparation
Monooleic glycerides are produced by the ester of fatty acids, mainly oleic acids, with glycerides. Since fatty acids are not pure substances but mixtures of fatty acids, the products produced by esterification will be mixtures of esters, including monostearate and monopalmitate. You have diesters and triesters. As a result, the physical properties of the glycerol monoleate will vary from manufacturer to manufacturer, for example, with melting points ranging from 10 to 35℃.
Safety
Monoolein is used in oral and topical preparations and is generally considered relatively non-toxic and non-irritating.
Incompatibilities
Monoolein glyceride has incompatibility with strong oxidants. Self-emulsifying grade incompatibility with cationic surfactant.