Cholic acid

Category

Polymer Solid Dispersant; Emulsifier

Molecular Formula

C24H40O5

Molecular Weight

408.32

Grade

Pharmceutical Excipients

UNII

NA

Chemical Name

/

CAS Number

81-25-4

Synonyms

Cholalic Acid

Stability and Storage Conditions

Keep sealed and away from light in a cool and dry place.

Source and Preparation

All kinds of cholic acids can be combined with glycine or taurine with peptide bonds to form various bile acids. The bile of pig, cow and sheep was hydrolyzed with cholecylanin and alkali, and the pH was adjusted to 3.0 with hydrochloric acid. The precipitates were extracted and washed to neutral, refined with ethanol and activated carbon, washed with glacial acetic acid, and recrystallized. There are several kinds of cholic acids due to the different number and location of hydroxyl groups. The main ones are 3, 7, 12-trihydroxycholic acid and deoxycholic acid (i.e. 3, 12-dihydroxycholic acid).

Safety

This product is non-toxic, ADI 0~1.25MG/kg.

Incompatibilities

This product can be destroyed by oxidation when it meets an oxidant.