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Products
Azone
Product Details
Category
Surfactant
Molecular Formula
C18H35NO
Molecular Weight
281.48
Grade
Pharmceutical Excipients
UNII
NA
Chemical Name
1-dodecyl azocyclic heptanone 2-ketone
CAS Number
59227-89-3
Administration route
Administration by injection, oral administration, percutaneous administration, vaginal administration
Dosage Form
injection, oral, percutaneous , vaginal preparations
Stability and Storage Conditions
It is stable to heat, but not to acid and base. Other functional components in the formula may separate oil from water.
Source and Preparation
It is prepared by the reaction of bromododecane with caprolactam in the presence of strong bases such as metallic sodium and sodium hydroxide, or in the condition of phase transfer catalysis of quaternary ammonium salts.
Applications
Azone, as an efficient skin penetration enhancer and a new type of non-ionic surfactant, has been widely applied in the fields of medicine, daily chemical, pesticide, printing and dyeing, chemical fiber, leather and so on.
Safety
When the concentration is less than 50%, it has no irritation to the skin. It is a non-toxic, safe and efficient transdermal absorption promoter.
Incompatibilities
Incompatibility with strong acid drugs, vaseline, etc.
Online Inquiry
Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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