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Aluminum Oxide
Product Details
Category
Adsorbents; Dispersants
Molecular Formula
Al2O3
Molecular Weight
101.96
Grade
Pharmceutical Excipients
Description
Aluminum oxide occurs as a white crystalline powder. Aluminum oxide occurs as two crystalline forms: a-aluminum oxide is composed of colorless hexagonal crystals, and g-aluminum oxide is composed of minute colorless cubic crystals that are transformed to the a-form at high temperatures.
UNII
LMI26O6933
Chemical Name
Aluminum oxide
CAS Number
1344-28-1
Synonyms
Activated alumina; activated aluminum oxide
Dosage Form
Oral tablets and topical sponge
Stability and Storage Conditions
Aluminum oxide should be stored in a well-closed container in a cool, dry, place. It is very hygroscopic.
Applications
Aluminum oxide is used mainly in tablet formulations. It is used for decoloring powders and is particularly widely used in antibiotic formulations. It is also used in suppositories, pessaries, and urethral inserts. Hydrated aluminum oxide is used in mordant dyeing to make lake pigments, in cosmetics, and therapeutically as an antacid.
Safety
Aluminum oxide is generally regarded as relatively nontoxic and nonirritant when used as an excipient. Inhalation of finely divided particles may cause lung damage .
Incompatibilities
Aluminum oxide should be kept well away from water. It is incompatible with strong oxidizers and chlorinated rubber. Aluminum oxide also reacts with chlorine trifluoride, ethylene oxide, sodium nitrate, and vinyl acetate.
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