Polymer Nanoparticles for Drug Delivery Services

Polymer nanoparticles are prepared using natural polymers or synthetic polymers, allowing the fabrication of polymer nanoparticles with different compositions and structures. The most common forms of polymeric nanoparticles are nanocapsules and nanospheres, which have several subclasses such as vesicles, micelles and dendrimers. The use of nanoparticles as drug carriers can achieve targeted delivery and slow-release drug delivery, which is due to the fact that small particles can enter many human organs and tissues that are difficult for large particles to enter, and can cross many biological barriers to reach the focal site. The main methods for preparing polymer nanoparticles are: (1) post-dispersion of polymers to form nanoparticles; (2) polymerization of monomers to form polymer nanoparticles; and (3) self-assembly of structurally ordered amphiphilic polymers in aqueous media to form nanoparticles.

Advantages of Polymer Nanoparticles

• The high molecular weight of the polymer, which allows the drug to remain in the lesion site for a longer period of time as a carrier.
• The drug inside the polymer nanoparticles can achieve slow or controlled release through diffusion or degradation of the polymer itself;
• Some functional components with targeting or controlled release can be chemically bonded to the polymer surface;
• If biodegradable polymer materials are used, the accumulation of carrier materials in human organs and tissues after drug release can be avoided, resulting in toxic side effects.

Our Services

CD Formulation has a long history of providing drug development and related services to pharmaceutical companies. Due to the nature of polymer nanoparticles in drug delivery, we can provide product performance testing and nanoparticle modification services to enhance their role in the drug industry.

Polymer Nanoparticle Performance Characterization

CD Formulation can provide customers with polymer nanoparticle particle size, morphology and material structure analysis, relative molecular mass, particle stability, phase change and thermal properties testing.

Nanoparticle Surface Modification Services

CD Formulation offers polymer nanoparticle modification services. Our specialized chemistry, biology and pharmacology experts have the technology to modify polymer nanoparticles in a variety of ways, including the addition of modifiers during synthesis, grafting on the polymer surface after nanoparticle synthesis and the formation of core-shell structures.

We can also provide other services related to polymer nanoparticles:

• Construction Services for Polymer-Drug Conjugated Micelles Delivery Systems
• Customization and Modification for Dendrimers
• Polymersomes Development
• Polymer Nanosphere Modification

Applications of Polymer Nanoparticles

Polymer nanoparticles provide a wide range of drugs through a number of delivery routes, such as small hydrophilic and hydrophobic drugs, vaccines, peptides and biomolecules.

About CD Formulation

CD Formulation provides integrated innovation solutions from strategy to implementation to help you increase opportunities and address challenges. Through our in-depth experience in many different industries, including consumer and technology, we bring innovative solutions and cross-industry best practices to drug development. If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.