Natural Polysaccharide Development Services

CD Formulation specializes in developing innovative natural polysaccharide solutions, dedicated to advancing the forefront of nucleic acid drug delivery technology. We leverage advanced polysaccharide modification techniques to develop efficient and safe delivery vectors aimed at improving the stability and delivery precision of nucleic acid drugs.

Why Develop Natural Polysaccharides for Drug Delivery?

Natural polysaccharides serve as ideal carriers for nucleic acid drug delivery. They not only effectively protect easily degradable nucleic acid drugs but also significantly enhance delivery efficiency. By forming stable polysaccharide-nucleic acid complexes, our solutions improve intracellular delivery and controlled release of drugs. Through chemical modifications, we further improve the targeting capabilities and bioactivity of polysaccharide carriers, addressing the precise delivery needs of various therapeutic uses. In this context, natural polysaccharides are advancing the application of nucleic acid drugs and accelerating the progress of gene therapy and the development of nucleic acid vaccines.

Fig.1 Introduction of natural polysaccharides. (CD Formulation)

Explore Our Natural Polysaccharide Development Services

Our Solutions of Natural Polysaccharide Development Services

In natural polysaccharide development services, we offer comprehensive solutions covering every phase from drug design to production.

Drug Loading Design

Initially, we conduct an in-depth analysis of the chemical properties of the drug and polysaccharides to select suitable polysaccharide types as carriers. Using optimized ratios and conditions, we ensure the drugs are uniformly distributed and integrated within the polysaccharide network, ensuring effective drug loading.

Drug Encapsulation Efficiency Analysis

We use techniques such as HPLC or UV to determine the actual drug content, compared to the initial input, to calculate encapsulation efficiency. This step helps in optimizing the preparation process to improve encapsulation efficiency.

Quality Control

Production is closely monitored to ensure polysaccharide purity, consistent drug loading, and precise particle size, using techniques such as DLS and SEM for thorough characterization.

Mass Production

We design scalable production processes to ensure the transition from laboratory results to commercial scale. This includes the control of reaction conditions and the application of continuous flow technology to improve yield and consistency.

Our Workflow of Natural Polysaccharide Development Services

Fig.2 Flow chart of natural polysaccharide development. (CD Formulation)

• Extraction and Purification

Harvest natural polysaccharides from sources like plants or microbes and cleanse them to get rid of unwanted impurities.

• Chemical Modification

Alter polysaccharides chemically to boost their stability, solubility, and interactions with nucleic acids, enhancing delivery effectiveness.

• Complex Formation

Link the modified polysaccharides with nucleic acids (like DNA, RNA) to create stable complexes, protecting nucleic acids from degradation prior to delivery.

• Characterization and Testing

Utilize techniques like NMR, FTIR, etc., for detailed characterization of the formed complexes and conduct bioactivity tests to evaluate their delivery efficiency and safety.

• In Vivo Evaluation

Test the polysaccharide-nucleic acid complexes in animal models to assess their distribution, effectiveness, and biocompatibility within biological systems and optimize based on results.

Our Technology Platforms

Our Advantages of Natural Polysaccharide Development Services

• We customize development plans based on clients' needs, from concept to implementation.
• Our expert team, including chemists and engineers, pushes innovation and speeds up projects.
• Advanced techniques improve polysaccharide functionality, maintaining market leadership.
• Rigorous quality controls ensure consistent, reliable products for large-scale deployment.

Publication Data

CD Formulation leads in natural polysaccharide development for nucleic acid drug delivery, offering innovative solutions. Our tailored services, expert team, and strict quality control guide clients from R&D to production, aligning scientific and commercial goals. Feel free to contact us, and our team looks forward to providing you with professional support.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.