Here's how you can reach us...
  • Tel:
  • Email:

Gel Transdermal Formulation Development

Inquiry

Gel-based transdermal formulations offer an efficient route for drug administration to the skin, mucous membranes, and cavities. These formulations are typically solutions, suspensions, or emulsions combined with non-toxic, biodegradable excipients to form semi-solid or thick liquids. The preparation process is straightforward, and the formulations have applications in dermatology, ophthalmology, and gastrointestinal health. By targeting affected areas, transdermal gels improve drug efficacy and reduce systemic side effects, making them a preferred choice for localized treatment. At CD Formulation, we specialize in supporting transdermal gel development, leveraging advanced scientific methods to provide effective, convenient drug delivery systems.

Advantages of Gel Transdermal Formulations

Gel transdermal systems ensure continuous drug release and penetration by applying medication directly to the skin. Key benefits include:

  • Enhanced Bioavailability: Transdermal gels bypass gastrointestinal irritation and the liver's first-pass metabolism, delivering drugs directly to the site of action.
  • Minimized Side Effects: Direct skin application reduces systemic drug distribution and metabolism, lowering the risk of side effects.
  • User Comfort: The gel's viscosity and spreadability allow easy application, providing patients with a comfortable treatment experience.

Figure 1. Skin structure and drug transport pathways during topical anticancer treatment.Fig.1 Skin structure and routes of drug transport through cancerous skin after topical anticancer treatment. (Marta Slavkova, et al. 2023)

What Can We Offer?

Fig.2 Various types of gel transdermal formulations developed at CD Formulation.Fig.2 Kinds of Gel Transdermal Formulation Development (CD Formulation)

Our Workflow for Gel Transdermal Formulation Development

  1. Initial Consultation: We assess your formulation needs and determine the appropriate gel type and drug properties.
  2. Drug Screening: Using cutting-edge technology, we screen potential drug candidates for transdermal delivery.
  3. Formulation Design: We optimize the formulation for stability, permeability, and biocompatibility using our expertise in gel matrix innovation.
  4. Development & Testing: Through intelligent automation and precise control, we ensure consistent and scalable production of transdermal gels.
  5. Final Evaluation: Advanced analytical techniques are employed to validate the formulation's quality.

Our Technology Platform

Techniques & Platform Specifics
Drug Solubilization
  • Nanotechnology
  • Solid dispersion
  • Microemulsion
  • Inclusion techniques
Analytical Tools
  • SEM (Scanning Electron Microscope)
  • TEM (Transmission Electron Microscope)
  • HPLC (High-Performance Liquid Chromatography)
  • LCMS/MS (Liquid Chromatography-Mass Spectrometry)

Why Choose CD Formulation?

  • A dedicated R&D team focused on high-quality, biocompatible materials for transdermal gels.
  • Advanced drug analysis tools for in-depth studies on drug properties, skin permeability, and patient-specific conditions.
  • Precision measurement of gel attributes, including appearance, viscosity, drug concentration, and permeability.

Published Data

Technology: Technology for Gel Transdermal Formulation Development

Journal: Gels

IF: 4.6

Published: 2023

Results: This systematic review aims to identify the most commonly used techniques for topical drug delivery using gel-based topical formulations in skin cancer treatment. The excipients used, the preparation approaches, and the methods characterizing gels are discussed in brief. The safety aspects are also highlighted. The combinatorial formulation of nanocarrier-loaded gels is also reviewed from the perspective of improving drug delivery characteristics. Some limitations and drawbacks in the identified strategies are also outlined and considered within the future scope of topical chemotherapy.

Our gel formulation development, using the world's leading nanotechnology, ensures that the active ingredient can efficiently and stably penetrate the skin or mucosal barrier, directly to the lesion or the target tissue, achieving precise treatment and deep nourishment. Whether skin care, pain management, or drug delivery systems, we strive to be exact, efficient, and safe. If you have any needs, please feel free to contact us and our colleagues will reply to you within three working days.

References

  1. Marta Slavkova, Borislav Tzankov, et al. Gel Formulations for Topical Treatment of Skin Cancer: A Review. Gels. 2023, 9, 352.
How It Works
STEP 2
We'll email you to provide your quote and confirm order details if applicable.
STEP 3
Execute the project with real-time communication, and deliver the final report promptly.
Related Services
Inquiry

CD Formulation is a global force in transdermal delivery and manufacturing. We provide a wide range of contract development and manufacturing services that are specifically designed to cater to...

Learn More

  • Tel:
  • Email:

Stay up to date with our latest releases of new research and promotions.

Copyright © CD Formulation. All Rights Reserved.