CD Formulation has developed a platform for delivering drugs using lipid nanoparticles, designed to effectively transport various nucleic acid treatments such as mRNA, siRNA, and ASOs. This system utilizes robust lipid configurations to enhance the stability of these drugs within the body and ensures precise cell targeting, thus overcoming traditional delivery obstacles and speeding up the research and development phase.

Why Choose Lipid Nanoparticles for Nucleic Acid Drug Delivery?

Lipid nanoparticles (LNPs) are valued for transporting nucleic acid therapeutics due to their exceptional properties and biological compatibility. They protect medications from enzymatic degradation and facilitate efficient delivery by integrating with cellular membranes. Their design is adaptable, allowing for optimization according to different types of nucleic acid drugs to enhance delivery efficiency and stability. Furthermore, LNPs significantly reduce the risk of immune response, increasing drug safety and tolerability. As such, LNPs have become the ideal choice for nucleic acid drug delivery, especially in applications requiring precise targeting and large-scale delivery, where they exhibit unrivaled advantages.

Fig.1 Characteristics of LNPs. (CD Formulation)

Our Solutions for Lipid Nanocarrier Drug Delivery Platforms

Delivery of ASOs Drugs

Our LNP platform efficiently delivers ASOs, ensuring high encapsulation efficiency and stability through optimized lipid encapsulation technology. The platform is designed to accommodate the chemical properties of ASOs, providing precise gene regulation capabilities within cells to improve bioavailability.

Delivery of siRNA Drugs

For siRNA delivery, our platform ensures high efficiency and low toxicity through refined particle size control and lipid composition. LNPs protect siRNA from degradation within the circulatory system while ensuring effective release within target cells, achieving precise gene silencing.

Delivery of mRNA Drugs

We offer optimized LNP solutions for mRNA drug delivery, enhancing mRNA stability and intracellular transport efficiency to support a wide range of gene expression applications. With unique lipid modulation, the platform easily adapts to different mRNA molecule sizes and characteristics, promoting innovative applications in vaccine therapy.

Delivery of Aptamers Drugs

Our platform supports efficient delivery of aptamers, improving their targeting binding capacity and stability in vivo through customized LNP structures. LNPs help aptamers cross biological barriers to specific target cells, regulating complex biological processes and paving the way for precision medicine.

Technical Support of Our Platform

R&D Laboratory

Our R&D laboratory is equipped with advanced technology to conduct comprehensive formulation development and process optimization. The laboratory includes a multi-channel micro-mixing system capable of efficiently producing samples on various scales.

Analytical Support

Our analytical services ensure high-quality control throughout R&D to production. This covers developing and validating methods, process control, quality assessment of raw materials and finished products, and conducting stability studies in line with international standards.

Testing Platforms for Lipid Nanoparticles

• DLS Platform
• HPLC Platform
• Zeta Potential Analysis Platform
• DSC Platform

Highlights of Lipid Nanoparticle Drug Delivery Platform

• Rapid Transition Capability

The platform design effectively accelerates projects from the R&D stage to clinical trials and commercial production, shortening the development cycle.

• Flexible Production Scale

The modular production system flexibly adjusts to support varying needs from small-scale experiments to large-scale production, meeting diverse project requirements.

• Comprehensive Technical Support

From formulation development to process optimization, the platform provides comprehensive technical support and analytical services to ensure product quality and compliance.

• Customized Solutions

With extensive experience and resources, the platform offers tailored delivery solutions based on the characteristics of various nucleic acid drugs to achieve optimal outcomes.

Services Provided by the Lipid Nanoparticle Drug Delivery Platform

CD Formulation's lipid nanoparticle nucleic acid drug delivery platform provides comprehensive customized services, aiming to create precise and efficient drug delivery systems for clients. By combining the latest nanotechnology with extensive practical experience, we formulate solutions that best meet project needs.

Publication Data

CD Formulation's platform is dedicated to providing efficient and customized lipid nanoparticle nucleic acid drug carrier solutions, helping to advance your project from research to large-scale production. Our team is dedicated to ensuring project success, providing expert technical support and flexible service models. For collaboration or more information, please contact our experienced professionals.