Methanol Test for Cosmetics

Methanol is used in cosmetic formulations mainly as a vehicle or solvent. It has a simple chemical structure, so it can easily dissolve many other ingredients in itself. Another use of methanol is as a denaturant. It typically find it used in denature ethyl alcohol common in many cosmetic products. Ethanol can be used as a solvent, defoamer in cosmetics, and the main reason for methanol exceeding the standard is caused by its raw material ethanol. Methanol has a strong stimulating effect on the respiratory tract and mucous membrane, and can be absorbed through the respiratory tract and skin. It is a restricted toxic substance in cosmetics. Therefore, methanol residues in cosmetics are increasingly valued by consumers.

Toxicity for Methanol

Studies in recent years have shown that methanol inhibits some oxidative alcohol systems in the body, inhibits the aerobic decomposition of sugar, causes the accumulation of lactic acid and other organic acids, and causes acidosis. Methanol mainly acts on the central nervous system, has obvious remote anesthesia effect, can cause cerebral edema, has a special selective effect on optic nerve and retina, causes optic atrophy, and leads to blindness in both eyes.

The skin absorption of methanol was studied by monkeys and others, and it is speculated that it is dangerous for humans to absorb 30 mL of methanol. Acute toxicity:

LD₅₀ (oral) human: 1400 mg/kg

LD₅₀ (inhalation) human: 4000 mL/L.

Because methanol is highly toxic, the content of methanol in cosmetics should be strictly controlled.

The Standard Test Method for Methanol in Cosmetics

Currently, the standard test method for methanol in cosmetics is distillation gas chromatography. In addition, solid-phase micro-extraction-gas chromatography, head-space gas chromatography, and colorimetry can also detect methanol.

The gas chromatography for methanol test method in cosmetics is as follows.

After gas-liquid equilibrium, direct extraction or distillation, the sample is separated by gas chromatography, detected by hydrogen flame ionization detector, qualitative according to the retention time, quantitative by peak area, and calculated by the standard curve method.

 Our Services

CD Formulation can provide you with testing services for methanol in cosmetics, and further evaluate the safety of cosmetics by testing the content of methanol in cosmetics. Whether you are a manufacturer, distributor or consumer, we have a professional methanol testing service team to complete your methanol test report in the quickest way possible.

Our Advantages

CD Formulation can provide comprehensive professional, impartial and high-quality cosmetic testing services, and is committed to providing meaningful and influential testing services for hazardous substances in cosmetics.

• With a high degree of industry recognition in bioformulation and cosmetics.
• With strong hardware strength, our company is equipped with large precision analytical instruments, which can meet various testing requirements.
• With a strong technical team and professional background technicians.
• CD Formulation can customize professional services that fully meet your requirements.

You only need four steps to easily solve your requirements.

How to Contact us?

If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.

Reference

1. Regulation (EC) No 1233/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products.