Lotions

Lotions generally refers to the liquid preparation for skin or cavity daubing or cleaning, which is extracted by appropriate methods. Water and ethanol are usually used as dispersing media. There may be separation of oil phase and water phase when emulsion lotion is stored, but it should be easily redistributed after shaking: the sediment after suspension lotion is placed should be easy to disperse and have enough stability after shaking; the lotion that is easy to deteriorate should be configured before use. Generally, lotion has the functions of cleaning, disinfection, antipruritic, astringency and protection. Commonly used benzyl benzoate lotion, calamine menthol lotion, etc.

Fig.1 Calamine lotion is used to treat itching(wikipedia).

The team of CD Formulation is leading experts in all aspects of pharmaceutical formulation development and dosage form optimization, we can accord the characteristics of the API and the development goals of the customers to design the formulation of lotions. CD Formulation can provide you with one-stop services to meet your needs of lotions.

Properties of Lotions

• Most lotions are water or water alcohol systems; a small amount of alcohol is added to help dissolve the active ingredients and accelerate the evaporation of the solvent from the skin surface.
• Most acne lotions are water alcohol that evaporates quickly, they are not sticky and dry.
• Emulsion type lotion is usually not dry, depending on water content (higher water and/or less oil will make drying drier).
• Lotion is easy to spread on large areas.
• Lotion is suitable for hair area, prone to folliculitis / acne skin, trigeminal region.

The Process of Developing Lotions

The lotion can be prepared in the following ways:

(1) Grind the ingredients into a smooth paste, then carefully add the remaining liquid phase or large amount using a high-speed mixer or homogenizer. The classic example is the Calamine emulsion, consisting of fine powdered insoluble solids and retained in more or less permanent suspensions due to the presence of suspending agents and / or surfactants.

(2) Through chemical interactions in liquids. For example: the second lotion approved by USP XVII is a surfactant stabilized O/W type.

If you have a requirement about lotions services, please contact us by phone or email, our colleagues will reply to you within three working days.

Reference

1. Shah S, Hussain T, Ikram U, et al. Formulation Study of Topically Applied Lotion: In Vitro and In Vivo Evaluation[J]. Bioimpacts, 2013, 3(1): 11-19.