Hydrogel Forming Microneedles Development Services

Hydrogel forming microneedles are prepared from a hydrogel polymeric matrix, and this microneedle array rapidly absorbs interstitial fluid upon insertion into the skin, causing the hydrogel to swell, creating continuous open pores within the gel where the drug penetrates and diffuses through the tissue fluid into the skin tissue. There are two forms of drug delivery for hydrogel forming microneedles: pre-positioned at the base of the microneedle, and drug and material together to form a needle body. In either case, the drug is delivered into the body via a channel after the hydrogel has absorbed water to form a delivery channel.

Fig.1 Schematic diagram of hydrogel forming microneedles. (Turner et al., 2021)

Features of Hydrogel Forming Microneedles

• High drug loading capacity and controlled drug release effect.
• Needle body material composed of polymeric biomaterials with good biocompatibility, avoiding potential damage to the skin caused by needle tip breakage.
• Microneedles prepared with cross-linked polymeric biomaterials can achieve subcutaneous dissolution of the microneedle without dissolution, which in turn increases the drug loading capacity of the microneedle.

Our Services

CD Formulation provides research and development of hydrogel forming microneedles technology, aiming to provide advanced hydrogel forming microneedles transdermal technology solutions for customers in the healthcare field. CD Formulation provides customized hydrogel forming microneedles drug development services and process development services in conjunction with competitive market dynamics, helping pharmaceutical companies to develop efficiently in the healthcare field.

• Drug Discovery Services

CD Formulation's professional pharmacologists have rich experience in biologic and chemical drug research, as well as advanced laboratory instrumentation to provide preclinical pharmacological research solutions and support innovative drug delivery routes for our clients.

• Process Development Services

In the process of integrated drug development and drug delivery using hydrogel forming microneedles technology, CD Formulation can provide professional process optimization guidance advice and solutions to help clients solve problems encountered in each process, providing R&D support for the process from drug development to the final drug delivery pathway into the patient's body in an efficient manner.

Application of Hydrogel Forming Microneedles

The therapeutic scope of hydrogel forming-based drug delivery systems has been extended to several pharmaceutical fields.

Our Advantages

• Personalized and Exclusive Services

Customized solutions for our clients, taking into account the current market situation.

• Quality Assurance

Advanced laboratory instruments and equipment, equipped with clean and sterile workshop, strict quality management system, efficient guarantee of product quality and service quality.

• Professional Team

Professional counterpart scientific researchers, many research results, with cutting-edge technology.

• Efficient Delivery Efficiency

If you have a requirement about our hydrogel forming microneedles technology research and development services, please contact us by phone or email, our colleagues will reply to you within three working days.

Reference

1. Turner, Joseph G., et al. Hydrogel-Forming Microneedles: Current Advancements and Future Trends[J]. Macromolecular Bioscience, 2021, 21(2): 2000307.