Gold Nanoparticle Drug Delivery System Development

Gold nanoparticles are an important class of materials used in bioimaging and photothermal therapy. They have surface plasmon resonance, light scattering and photothermal properties and small size effect, and can be loaded with a large number of small molecules and gene drugs through reasonable surface modification, and can be used in drug delivery system by taking advantage of the high permeability and retention effect of solid tumors to enter the tumor tissue.

The main advantages of gold nanoparticles as drug carriers are also shown in:

• The core is an amorous and non-toxic substance;
• The particle size can be controlled from 1 to 150 nm by regulating the preparation conditions;
• The surface can be modified by a variety of functional groups, i.e., multifunctional modification, which can be used to obtain a variety of application properties, such as active targeting and chemical stimulation-sensitive release (e.g., glutathione-induced release or pH-sensitive release);
• The solubility of insoluble drugs can be increased by binding to them after reasonable modification;
• By using its special surface plasmonic co-oscillation, light scattering and photothermal properties, it can be used to track the intracellular distribution of drugs through cellular imaging, and can effectively achieve light-mediated drug release.

Our Services

Custom Synthesis Services

Customized gold nanoparticle-liposome systems, CD Formulation focuses on the screening of complexes that meet the requirements of preventing aggregation of gold nanoparticles on the one hand, and performing liposome imaging and photo-mediated drug release studies on the other.

For customization of gold nanoparticle-micellar systems, we provide a range of services for this micellar system, including screening of micellar surface linkers.

Customization of gold nanoparticle-nanosphere system, we can modulate the surface charge of nanospheres, which in turn can modulate the membrane penetration efficiency, nuclear targeting and cytotoxicity of this system.

Customization of gold nanoparticle-drug conjugates, CD Formulation can combine gold nanoparticles and drug molecules (biologics, chemical drugs, etc.) to build drug delivery systems.

Characterization Testing Services

CD Formulation provides professional instrumentation to characterize gold nanoparticles or their modifications, including morphology testing, drug loading testing, etc.

Solutions Offering

For the problems faced by customers in the drug development process, CD Formulation's professional research team can provide support to offer solutions for your products.

About CD Formulation

CD Formulation provides integrated innovation solutions from strategy to implementation to help you increase opportunities and address challenges. Through our in-depth experience in many different industries, including consumer and technology, we bring innovative solutions and cross-industry best practices to drug development. If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.