Cell-based Assays for Cosmetics

As a supplier of cosmetic products and services, CD Formulation offers a full range of integrated cosmetic services, from testing for toxic and hazardous substances and efficacy testing to OEM services for cosmetic products. Together with internationally recognized laboratories, CD Formulation performs all tests in a complete and reliable manner within the scope of cosmetic cell testing.

Background

The human skin and its appendages are the main medium of use for cosmetics and the most intuitive vehicle to reflect the use and efficacy of cosmetics. For the safety and efficacy evaluation of skin cosmetics, in vitro cultures of various types of skin cells such as human or mouse melanoma cells, fibroblasts, keratin-forming cells, are generally used. For other cosmetic products such as hair and body products, endothelial cells, epithelial cells, adipocytes, and hair papilla cells are also used for safety and efficacy evaluations. For different efficacy and evaluation needs, specific cells are cultured or cell damage models are established in vitro, stimulated with target ingredients, cell morphology and toxic proliferation indicators are observed, and the efficacy of raw materials or finished products is evaluated by molecular biology means such as analysis of specific gene pathways and related protein expression. Due to the low economic cost, short experimental cycle, relatively stable subjects and mature operation methods, the application of cell biology methods to establish in vitro cultured skin cell models has become one of the mainstream methods for cosmetic raw material screening and efficacy evaluation of active substances.

The Role of Cell-based Assays

It can test different kinds of properties of cosmetics such as soothing, anti-wrinkle, firming, repairing, oil control, whitening, acute toxicity, phototoxicity and mutagenicity.

Our Services

The cosmetic safety evaluation system includes: classical toxicology tests, in vitro genotoxicity tests and human safety tests. Toxicological studies, such as eye irritation, skin irritation and skin sensitization, which are key in the safety evaluation of cosmetics, are based on animal testing as a whole. In addition, the models used for cosmetic efficacy studies focus on mice, guinea pigs, and rabbits. CD Formulation also provides customers with melanoma cells, fibroblasts, and keratin-forming cells from mice, as well as endothelial cells, epithelial cells, adipocytes, and hair papilla cells, to ensure that customers have the cells they need.

Services contents

• Cell-based assays for skin care types
• Cell-based assays for hair care types
• Cell-based assays for body types

In addition to the above tests, we are constantly developing new types of business to help you better test the efficacy of your products.

If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.