Transdermal Patches Drug Delivery System Services

Transdermal patches are medicinal adhesive patches that are applied to the skin and used to deliver a specific amount of medication through the skin into the bloodstream. Transdermal drug delivery systems are drugs administered topically as patches that deliver drugs at a predetermined and controlled rate for systemic effects. Theoretically, transdermal patches work on a very simple principle. The drug is administered at a relatively high dose to the inside of the patch, which is worn on the skin for an extended period of time. Through a diffusion process, the drug passes directly through the skin into the bloodstream. Due to the high concentration on the patch and the low concentration in the blood, the drug will continue to diffuse into the bloodstream for a long time, keeping the drug concentration in the bloodstream constant.

Advantages of Transdermal Patches

• Avoidance of hepatic first pass effects resulting in better bioavailability and fewer side effects for molecules with low oral bioavailability.
• In certain therapeutic areas and in certain patient groups, self-administered transdermal patches can reduce pill burden and provide longer dosing intervals and ease of administration, thereby improving patient compliance.
• Continuous dosing throughout the application, avoiding potential drug spikes and periods of over- and under-dosing, thus allowing for less frequent dosing.

Our Services

Transdermal Patches Development

CD Formulation can help you assess the suitability of your drug for transdermal application by analyzing key physicochemical properties of the drug molecule and performing preliminary in vitro and ex vivo permeation studies. Our company has specialized laboratory equipment and experienced drug developers to perform transdermal patch development that can improve bioavailability and reduce side effects, while improving patient compliance.

Transdermal Patches Drug Delivery System Services

As a leading expert in the full range of transdermal patch drug delivery services, we excel in all aspects of drug delivery, from simple projects to the most complex patches on the market. CD Formulation offers drug delivery system services including:

• Adhesive Dispersion-Type System with Adhesive Development
• Customized Membrane Permeation Controlled Systems
• Design Services for Matrix Diffusion-Controlled Systems
• Development and Optimization of Micro-Reservoir Controlled-Release Drug Delivery Systems

Our Experience

Our transdermal patch experience extends to all types of patches, including matrix, reservoir and complex multi-material patches, etc. Also, we can work in a variety of therapeutic areas, including pain and central nervous system.

About CD Formulation

CD Formulation provides integrated innovation solutions from strategy to implementation to help you increase opportunities and address challenges. Through our in-depth experience in many different industries, including consumer and technology, we bring innovative solutions and cross-industry best practices to drug development. If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.