Microencapsulation Drug Delivery System Services

Microencapsulation technology refers to the use of natural or synthetic polymeric compound materials to make capsule wall shells (films) in which drugs (synthetic, semi-synthetic, biological products) are encapsulated in a capsule membrane and released at a controlled rate only under specific conditions. This technique has no effect on the original chemical properties of the drug, and the drug is released for therapeutic purposes by some external stimulation or slow release. Microcapsules generally have a diameter of 1 to 500 μm and a wall thickness of 0.5 to 150 μm. Microcapsules have the ability to improve and enhance the appearance of substances and their properties, store microscopic substances, delay and control release, and protect the core material from the environment, reduce toxicity, and shield it from odors.

Preparation Options for Microcapsules

Chemical Method

Interfacial polymerization method, in situ polymerization method, sharp pore - solidification bath method.

Physicochemical Method

Condensed phase separation method, complex phase emulsion method.

Physico-Mechanical Method

Air suspension film formation method, spray drying method.

Our Services

CD Formulation provides microencapsulation technology services with researchers specializing in pharmacology and analytical chemistry who have extensive experience in the healthcare industry. Our services include microencapsulation performance evaluation and process solutions, which can help our clients develop drugs and drug delivery methods to accelerate commercialization and bring drugs to market as quickly as possible.

Performance Evaluation

Performance evaluation of microcapsules includes: surface morphology of microcapsules, core size, particle size distribution, microcapsule wall thickness, microcapsule core release performance, encapsulation rate, etc. Through a series of tests, the performance of microcapsules is evaluated to determine whether the microcapsules meet the requirements and regulations.

Process Solutions

CD Formulation provides process optimization services for microencapsulation technology, from the selection of microcapsule materials to the timing and quantity of core release, to help customers solve problems encountered in the development and design of microencapsulation technology.

Laboratory Instruments

• Optical Microscope
• Scanning Electron Microscope
• Transmission Electron Microscope
• Electron Microscope
• Spectrophotometer
• High Performance Liquid Chromatography
• Thermogravimetry
• Infrared Spectrometer

Application of Microencapsulation Technology in Pharmaceuticals

• Insulation that can mask offensive or undesirable odors, used for the delivery of fish oil, certain Chinese medicines, etc.
• Improve the safety of transported drugs and change the release behavior of drugs, used for the delivery of microencapsulated insulin, etc.
• Avoid deactivation and instability of drugs in the body, used in the delivery of testosterone, etc.

About CD Formulation

CD Formulation provides integrated innovation solutions from strategy to implementation to help you increase opportunities and address challenges. Through our in-depth experience in many different industries, including consumer and technology, we bring innovative solutions and cross-industry best practices to drug development. If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.