Polymeric Nanoparticles for Therapeutic Research
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CD Formulation specializes in the polymeric nanoparticle development process using the polymeric nanoparticle technology platform. We provide excellent polymeric nanoparticle customization services to support therapeutic research.
Advantages of Polymeric Nanoparticles in Therapeutic Research
Based on our rich experimental experience and strong technical strength, we can fabricate plenty of structural polymeric nanoparticles to accelerate nanoformulation development.
Fig.1 The structures of typical polymeric nanoparticles: (A) micelles, (B) dendrimers, (C) polymersomes, (D) hydrogels, and (E) metal-organic frameworks. (Xiao Xiao, et al. 2022)
- Good biocompatibility.
- Wide structural variability.
- Obvious biomimetic properties.
Applications of Polymeric Nanoparticles in Therapeutic Research
To enhance targeted drug delivery, we in-depthly analyze the properties, surface functions, and applications of polymeric nanoparticles, such as their unique structure and biocompatibility. They have widespread biomedical applications in targeted cells, ocular delivery, vaccine delivery, etc.
Polymeric Nanoparticles in Targeting Delivery
Polymeric nanoparticles can achieve targeted drug delivery, prevent unstable substances (including proteins, peptides, and DNA) due to their biodegradability, biocompatibility, non-toxicity, prolonged blood flow, and broad therapeutic drug loading spectrum, and regulate drug release. Using polymeric nanoparticle technologies, we develop targeted delivery systems to deliver targeted drugs.
Polymeric Nanoparticles in Cancer Therapy
Polymeric nanoparticles can overcome the problems of typical anticancer drugs, such as their poor water solubility, rapid elimination, and lack of selectivity, and reduce the degree of anticancer reaching cancer tissues. The targeted delivery system based on drug-loaded polymeric nanoparticles we created can be used to deliver anti-tumor therapies to targets in specific sites over a longer period of time for cancer therapy. Depending on our powerful nanotechnology platforms, host cytotoxic agents, small interfering RNA, chemosensitizers, and anti-angiogenic agents are designed and prepared to accelerate cancer studies.
Polymeric Nanoparticles in Cancer Diagnosis and Imaging
To discover effective initial detection, diagnosis, and treatment methods, we have developed polymeric nanoparticle delivery platforms. Polymeric nanoparticles can be used for cancer diagnosis and imaging, including breast, lung, colon, rectal, and prostate cancers, due to their ability to modify the surface and control the solubility of implants to image cancer cells.
Polymeric Nanocarriers in Ocular Drug Delivery
We leverage the leading polymeric nanocarrier technologies to synthesize special polymeric nanocarriers to deliver the drugs to the eye for treating ocular diseases.
Polymeric Dendrimer Nanocarriers in Neurodegenerative Diseases
Our customized polymeric dendrimers can promote cellular uptake into certain cell types and thus improve the bioavailability of drugs to treat neurodegenerative diseases.
Custom Polymeric Nanoparticle Development Service for Therapeutic Research
At our polymeric nanoparticle technology platform, CD Formulation has explored and researched multiple fabrication methods of polymeric nanoparticles in disease treatment, catering to customers' different requirements.
Liposome Development for Nanomedicine
CD Formulation has rich experience in researching and developing liposomes for different disease treatments. After our continuous experimental accumulation, we can customize personalized liposomes to cater to therapeutic research.
Polymeric Nanoparticle Development for Nanomedicine
CD Formulation is keen on the research of developing polymeric nanoparticles for disease treatment. At our platform, we are able to create personalized polymeric nanoparticles for different customers, thereby quickly promoting the progress of the preclinical therapeutic research of different diseases.
Polymeric Micelle Development for Nanomedicine
CD Formulation is also good at the development and research of polymeric micelles for different diseases. After exploring the polymeric micelle development process and the preparation methods, we can offer personalized different polymeric nanoparticle customization services for the therapeutic research of various diseases.
Nanogel Development for Nanomedicine
At our mature nanogel technology platform, CD Formulation has been committed to the development of nanogels for therapeutic research, especially eye therapy. We can provide customers with our professional nanogel development and customization services for different customers, promoting the special therapeutic research progress of nanogels.
Why Choose CD Formulation?
- Hold polymeric nanoparticle technology platform.
- Possess high-yield polymeric nanoparticle fabrication techniques.
- Have professional customization services for special polymeric nanoparticles in therapeutic research.
Published Data
Technology: 5-boronopicolinic acid (BA) modified tumor-targeting drug delivery systems (T-DDSs) with strong tumor-targeting function
Journal: Biomaterials Advances
IF: 5.5
Published: 2021
Results:
5-boronic acid (BA)-modified tumor-targeted drug delivery systems (T-DDSs) established by the authors have strong tumor-targeting functions. The extremely high targeting function and biocompatibility of T-DDSs improved their drug delivery efficiency and achieved good anti-tumor effects. This study shows that BA-modified T-DDS is used to design and prepare DDS with good biocompatibility and strong tumor specificity to improve drug delivery efficiency.
Fig.2 Preparation process of T-DDSs, selective drug delivery, and anti-tumor efficacy in a subcutaneous mammary tumor model. (Xuefang Hao, et al. 2021)
Polymeric nanoparticles are widely used in the treatment of various diseases due to their excellent biocompatibility, unlimited stability, which ensures sustained drug delivery, and their stimulus acceptance properties (such as temperature, pH, redox, and ionic strength), which enable precise control of intracellular substances. CD Formulation can offer various polymeric nanoparticle customization services for different therapeutic research, including liposomes, polymeric micelles, dendrimers, etc. If you are interested in our polymeric nanoparticle for therapeutic research, please do not hesitate to contact us.
References
- Xiao Xiao, Fei Teng, Changkuo Shi, et al. Polymeric nanoparticles -Promising carriers for cancer therapy. Frontiers in Bioengineering and Biotechnology. 2022,10:1024143.
- Xuefang Hao, Weiwei Gai, Lina Wang, et al. 5-Boronopicolinic acid-functionalized polymeric nanoparticles for targeting drug delivery and enhanced tumor therapy. Materials Science and Engineering: C. 2021,119,111553.
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