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Vitamin Oral Thin Film Formulation Research

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As an innovative formulation of vitamin supplements, vitamins oral thin film have been extensively studied. CD Formulation uses oral thin film technology to provide an alternative delivery system of health products, and we offer professional development research and production services of vitamins oral thin film for specific deficiency or health problems.

Main Application of Vitamins Oral Thin Film

The water-soluble vitamins include the vitamin B complex and vitamin C. The fat-soluble vitamins are vitamins A, D, E, and K. Lack of sufficient quantities of vitamins in the diet results in specific vitamin deficiency diseases. Our objective is to develop a broader range of vitamin oral thin film products based on our oral thin film technology platform, expanding the delivery pathway for vitamin deficiencies.

Applications Detailed Information
The Vitamins Buccal Mucoadhesive Film
Fig.1 Development of buccal mucoadhesive film for delivering vitamins.
Fig.1 The buccal mucoadhesive film for delivery of vitamins. (Umberto M. Musazzi, et al., 2019)
Improve the buccal delivery of vitamin B6.
Active Ingredients: Vitamin B6
Vitamin B6 is a model of a highly water-soluble, there are two main strategies that were combined. First, VB6 was entrapped in liposomes, formulated as mucoadhesive film. The vitamin B6 buccal mucoadhesive film provided faster initial permeation than the liquid forms.
Vitamin D3 Transdermal Film
Fig.2 Preparation and Evaluation of Vitamin D3 oral thin Film.
Fig.2 Preparation and Evaluation of Vitamin D3 Transdermal Film. (Majd Kittaneh, et al., 2023)
Active Ingredients: Vitamin D3
Vitamin D3 film is a promising delivery system for vitamin D3. It could provide an alternative for oral and parenteral routes.
Active Ingredients: Vitamin B12
The symptoms of vitamin B12 deficiency include megaloblastic anemia, persistent weakness, appetite loss, mood disorders, and birth defects in pregnant women. Vitamin B12 buccal film formulation can be considered an effective alternative portal with noninvasive and more convenient characteristics compared with the I.M. injection dosage form.

Vitamin Oral Thin Film Preparation

Vitamin Oral Thin Film Preparation Detailed Information
Fig.3 Coating and slitting manufacturing process of oral thin film.
Fig.3 Manufacturing steps of oral thin film. (Irma Elisa Cupone, et al., 2020)
Vitamin oral thin films usually are manufactured according to the casting method of different steps. Generally, a water-based mixture is prepared at first, under the control of the temperature and the stirring speed of the mixer. Afterward, the mixture is spread on the intermediate liner and dried in a drying tunnel, controlling temperature, air circulation, and coating speed. The roll of dry mass is submitted to the slitting process to cut the roll in the reels with the first dimension of the final surface of the films. In the last step, the thin films are punched, pouched, and sealed in suitable single-dose sachets using a pouch-forming and sealing machine.

Our Vitamin Oral Thin Film R&D Services

We offer comprehensive vitamins oral thin film formulation development research services, including formulation research, process optimization research, and scale-up manufacturing of oral thin films for vitamins.

Formulation Development

Our formulation development services include formulation design, excipients selection, process development, analytical method development, etc.

Process Optimization

We employ advanced techniques and technologies to optimize the manufacturing process of oral thin films, ensuring scalability and reproducibility.

Scale-up Manufacturing

We offer comprehensive scale-up manufacturing services for vitamins oral thin film. Our experienced team specializes in translating laboratory-scale formulations into full-scale production processes to meet our clients' commercial manufacturing requirements.

With our cutting-edge oral thin film delivery technology platform, CD Formulation offers one-stop vitamins oral thin film delivery systems research services. If you require our vitamins oral thin film services, please contact us by phone or email, and our colleagues will get back to you within three working days.

References

  1. Majd Kittaneh, Majd Kittaneh, et al. Preparation and Evaluation of Vitamin D3 Supplementation as Transdermal Film-Forming Solution. 2023, 15(1).
  2. Irma Elisa Cupone, Eleonora Dellera, et al. Development and Characterization of an Orodispersible Film for Vitamin D3 Supplementation. Molecules. 2020, 25(24).
  3. Heba Abd El Azim, Noha Nafee, et al. Liposomal buccal mucoadhesive film for improved delivery and permeation of water-soluble vitamins. International Journal of Pharmaceutics. 2024, Vol (488): 78-85.
How It Works
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STEP 3
Execute the project with real-time communication, and deliver the final report promptly.
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CD Formulation, an expert in novel oral thin film delivery systems, is dedicated to supporting pharmaceutical companies in developing and commercializing innovative drug formulations...

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