Solvent Casting Technology for Oral Thin Film Manufacturing

Oral thin films are thin, flexible films for drug delivery. There are many production methods, among which solvent casting is the most widely used technology for manufacturing oral thin film, which has low processing costs, straightforward application, and easy preparation. Our solvent casting technology is a cutting-edge method for oral thin film manufacturing, and this innovative technology allows for precise control over film thickness, uniformity, and drug distribution, resulting in high-quality, consistent products.

Fig.1 Solvent casting method. (RUCHITA BADEKAR, et al., 2024)

Advantages of Solvent Casting Technology

• Solvent casting technology is ideal for manufacturing films containing heat-sensitive active pharmaceutical ingredients (APIs) because the temperatures required to remove the solvents are relatively low compared to those needed for a hot-melt extrusion process.
• Better uniformity of thickness and bitter clarity than extrusion.
• The thin film has a fine gloss and freedom from defects like lines.
• The thin film has more flexibility and better physical properties.
• The cost of this method is also low.

Fig.2 Diagram of a Solvent-Casting Film System. (Ms. Prakruti M. Amin, et al., 2015)

Crucial Factors Involved in Using Solvent Casting Technology

Solvent casting is an ideal technology for manufacturing films containing heat-sensitive APIs because the temperatures required to remove the solvents are relatively low, and the preparation process is simple. Simply put, components that dissolve in water are made by combining them in a heated magnetic stirrer. The medication and additional excipients are added to this mixture to create a viscous solution. This method's solution is put into a petri dish, and the solvents evaporate. They are cut into pieces of the appropriate size based on the concentration of active ingredients they contain.

Fig.3 Crucial factors involved in manufacturing oral thin film using the solvent casting technology. (CD Formulation)

Explore the Preparation Process of Solvent Casting Technology for Oral Thin Film

Solvent casting technology is a widely used method for producing oral thin films, offering a versatile and efficient way to create flexible, rapidly dissolving oral thin film for drug delivery.

Why Choose CD Formulation?

• Our solvent casting technology allows for the creation of oral thin films with precise dosing.
• Our solvent casting technology enables the customization of oral thin films to incorporate various active pharmaceutical ingredients, enabling the creation of combination therapies or personalized medicine.
• Our solvent casting technology is suitable for manufacturing oral thin films at different production scales, making it adaptable for both small-scale and large-scale production.

Published Data

CD Formulation has extensive experience manufacturing oral thin film using solvent casting technology, providing in-depth knowledge and expertise to support our clients' needs. If you require our solvent casting technology for oral thin film manufacturing services, please contact us by phone or email, and our colleagues will get to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.