At CD Formulation, we excel in crafting targeted drug delivery systems that ensure precise and efficient transport of compounds to specified locations. Our advanced technologies and creative methodologies are tailored to meet the diverse needs of our clients, optimizing functionality and effectiveness.

Why Design Targeted Drug Delivery Systems (TDDS)?

TDDS aims to deliver drugs directly to specific sites within the body, using carriers to target particular organs or cells, ensuring prolonged presence and effectiveness. It features precise delivery, accumulation, regulated release, and compatibility with biological systems. The system can employ unique molecular tags for active delivery straight to cell targets, optimizing effectiveness while minimizing unwanted effects.

Fig.1 Advantages of targeted drug delivery systems. (CD Formulation)

Types of Targeted Drug Delivery Systems

Fig.2 Schematic of different types of carriers. (CD Formulation)

Explore Our Targeted Drug Delivery System Design Services

Design of Targeting Molecules in Carriers

PEGylation is a crucial method for achieving long circulation and targeting. In delivery carriers, both targeting molecules and PEG may coexist, linked in various ways to provide long-circulating and targeting properties.

Carrier-Mediated TDDS Development

Common carriers include micro-particles such as liposomes, emulsions, nanoparticles, or nanocapsules, each changing drug distribution and enhancing bioavailability, formulation uniformity, dispersibility, and absorption.

Antibody-Mediated TDDS Development

Utilizing peptides, monoclonal antibodies, and their fragments as targeting vehicles by covalent coupling or adsorption onto drug carriers, or forming conjugates with cytotoxic molecules, aims to selectively exert anti-tumor effects while minimizing normal tissue toxicity.

General Workflow for Targeted Drug Delivery System Design Services

Fig.3 Flow chart of targeted drug delivery system design. (CD Formulation)

• Requirement Analysis - CD Formulation's expert team conducts detailed discussions with clients to clarify specific needs, including target molecule characteristics, carrier material selection, and environmental considerations.
• Material Selection and Validation - Based on analyzed needs, suitable nanomaterials or other carrier materials are selected and validated to ensure compatibility and stability.
• System Design and Optimization - Following material selection, system structure design is performed, considering all influencing factors. Design is continually optimized through simulations and experiments to achieve optimal delivery efficiency.
• Testing and Adjustment - Small-scale experimental tests are conducted, with data feedback used to fine-tune the system, ensuring targeted performance meets standard expectations.

Nucleic Acid Drug Delivery Platforms

Our nucleic acid drug delivery platform, by offering advanced carrier technologies, has significantly advanced the development of targeted drug delivery systems. Our platform can be utilized to design efficient delivery mechanisms, ensuring that nucleic acid drugs precisely reach their target areas.

Our Advantages of Targeted Drug Delivery System Design Services

• Precision Crafting - Our services focus on designing solutions that precisely address client-specific regional needs.
• Systemic Interference Reduction - We specialize in tailoring delivery strategies that significantly lower unwanted systemic interactions.
• Custom Design Support - Our team is dedicated to providing flexible system design services that adapt to varied client requirements seamlessly.
• Resource Optimization - We offer service expertise that ensures minimal resource wastage through targeted delivery solutions.

Publication Data

CD Formulation offers support and consultation throughout initial design and subsequent development stages to optimize delivery system efficiency and performance. If interested in our targeted drug delivery system design services, please feel free to contact us.