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Gel Electrophoresis Technology Platform

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CD Formulation offers a cutting-edge and adaptable gel electrophoresis system tailored to address the diverse requirements of contemporary biological research. This platform supports a broad spectrum of analyses, encompassing both nucleic acids and proteins, thereby empowering researchers to obtain profound molecular insights through precise and high-resolution separation capabilities.

Features of Gel Electrophoresis Technology

Fig.1 Characteristics of Gel Electrophoresis Technology. Fig.1 Features of Gel electrophoresis technology. (CD Formulation)

Types of Gel Electrophoresis Technology Platform

PAGE Platform

PAGE (Polyacrylamide Gel Electrophoresis) separates small proteins and nucleic acids, achieving high resolution through adjustable gel concentration, and is widely used in molecular biology.

SDS-PAGE Platform

SDS (Sodium Dodecyl Sulfate) denatures proteins, minimizing the effects of shape and charge to allow separation by molecular weight. It is the standard method for accurate protein analysis and complex sample separation.

ITEP Platform

ITEP (Isoelectric Focusing Electrophoresis) separates proteins by their isoelectric points in a pH gradient, crucial for analyzing protein modifications and structures.

PFGE Platform

PFGE (Pulsed-field Gel Electrophoresis) enhances the resolution of large DNA fragments by changing the electric field direction. It is vital in epidemiology and microbial genomics for analyzing complex genetic issues.

Core Capabilities of Our Gel Electrophoresis Platform

Items	Descriptions
Versatile Molecular Separation	Our platform supports a broad range of molecular separation needs, from large DNA fragments to fine oligonucleotides, ensuring efficient separation for various laboratory requirements.
Advanced Medium Selection	We offer multiple electrophoresis media, including agarose and polyacrylamide gels, to suit biological molecules of different sizes and nature, ensuring adaptable application in diverse experimental conditions.
High-Precision Resolution	With outstanding resolution capabilities, our platform can discern subtle molecular differences in complex samples by optimizing electrophoresis conditions, providing profound molecular insights for research.
Sensitive Detection Methods	By incorporating high-sensitivity staining and detection techniques, our platform ensures the accuracy and repeatability of experimental results, providing reliable support for data analysis and verification.

Highlights of Our Gel Electrophoresis Technology Platform

System Integration - Our platform harmonizes with diverse lab equipment and software, providing a smooth and consistent experience for scientists.
Data Management - Featuring advanced data capture and analysis, users can monitor operations in real time, gaining comprehensive results for swift decision-making.
Eco and Safety - We emphasize the use of eco-friendly materials and safe protocols, reducing environmental impact while ensuring lab personnel safety.
Custom Support - We offer personalized technical support to help users fully leverage our platform, addressing specific research needs and project objectives.

Our Analytical Characterization Services

CD Formulation's gel electrophoresis platform plays a crucial role in the analysis and characterization of nucleic acid drugs, offering key services to support quality control and research and development.

Identification for Nucleic Acid Drugs

Our platform provides precise identification and purity testing of nucleic acid drugs to ensure they meet standards.

Structural Characterization for Nucleic Acid Drugs

Our platform's capabilities include sequence verification analysis to aid in understanding the biological activity of the drugs.

Physicochemical Characterization

By analyzing molecular weight and other metrics, our platform delivers comprehensive physicochemical profiling of drugs.

Impurity Analysis

Our innovative platform can effectively detect trace impurities in nucleic acid drugs, thereby ensuring their safety and efficacy.

Publication Data

Technology: PCR product analysis by Gel electrophoresis

Journal: Nature Microbiology

IF: 20.5

Published: 2023

Results:

An end-to-end workflow was designed and implemented in Ghana to detect the diversity of antimalarial drug resistance markers and vaccine target cyclosporin (csp) proteins in Plasmodium falciparum using nanopore sequencing. The authors analyzed 196 clinical samples and showed that our method is fast, robust, accurate and easy to implement. Importantly, authors' method can be applied to dried blood spot samples, which are easily collected in endemic settings. The authors' study demonstrates the feasibility of nanopore sequencing for malaria genomic surveillance in malaria-endemic countries.

Fig.2 Gel analysis of PCR amplifications. Fig.2 Gel electrophoresis of PCR products. (Girgis S T, et al., 2023)

CD Formulation's gel electrophoresis system is committed to offering accurate and dependable analysis for your nucleic acid drug studies. We're here to support you in fulfilling your R&D ambitions. To find out more or to ask about our services, please get in touch with our team.

References

Girgis S T, Adika E, Nenyewodey F E, et al. Drug resistance and vaccine target surveillance of Plasmodium falciparum using Nanopore sequencing in Ghana. Nat. Microbiol. 2023, 8(12): 2365-2377.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.

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