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Veterinary Spray Formulations Development

CD Formulation offers a one-stop solution for creating topical, nasal, and inhalable spray products. Backed by decades of expertise in propellant engineering and formulation design, whether the goal is optimized dermal penetration, targeted pulmonary delivery, or controlled dosing kinetics, our scientists will leverage their formulation expertise to develop innovative spray technologies that improve drug therapies for animals.

Spray Formulations for Veterinary Administration

Spray formulations offer significant advantages in administering veterinary drugs, especially to large animals. Compared to injections, sprays are non-invasive and reduce stress during treatment. Sprays also avoid complications from improperly injected needles. Topical sprays allow direct application to skin or mucous membranes for localized therapy. This achieves high drug concentrations at sites of infection or inflammation for enhanced efficacy.

How Do We Develop Veterinary Sprays?

Veterinary Topical Spray Development - CD Formulation

Use propane/butane or compressed air/nitrogen as non-toxic propellants.
Use penetrants to help active ingredients penetrate the skin/coat and distribute evenly.
Use solubilizers to aid the dissolution of the active materials.
Adjust pH for skin compatibility, usually around 5-7.
Test spray pattern, throughput, and microbial quality.

Use non-propellant water-based or alcohol-based systems.
Use a buffer such as isotonic saline to minimize stinging during application.
Check the viscosity to ensure it forms a fine mist without running off or dripping.
Ensure dose delivery is consistent and accurate.
Packed in a plastic bottle with a metering pump for precise dosing.
Test and confirm spray characteristics and sterility.
Evaluate pharmacology in animal experiments.

Veterinary Nasal Spray Development - CD Formulation

Veterinary Aerosol Development - CD Formulation

Use liquefied propellants like hydrofluoroalkane (HFA) for safety.
Use surfactants to help particles deposit deep in the lungs and coat lung surfaces evenly.
Use nanoparticles or microparticles to carry insoluble drugs.
Test plume geometry/droplet size distribution for proper lung deposition.
Conduct in vitro lung cell studies to test for toxicity and efficacy.
Evaluate in vivo in animal models for lung distribution and pharmacokinetics.

Our Spray Analysis Services

Laser Diffraction	By measuring how the spray scatters light to analyze droplet size distribution, laser diffraction can provide particle sizes as small as nanometers.
Spray Pattern Imaging	We visually characterize spray geometry and coverage using high-speed cameras and strobe backlighting.
High-Speed Imaging	Our specialized cameras capture fine droplet dynamics with microsecond resolution to evaluate atomization mechanisms and provide information on spray droplet size, distribution, and velocity.
Raman Spectroscopy	With Raman spectroscopy, we can identify the spray components and monitor the evaporation process.
Differential Mobility Analysis	We can classify nanodroplets by their electrical mobility.

Applications of Our Veterinary Spray Development Services

Respiratory Diseases

We can help customers develop nasal sprays for the treatment of respiratory diseases in animals. When administered through the nasal mucosa, the drug works quickly to relieve symptoms.

Skin Disease

For skin diseases, such as fungal infections, we can treat them with antifungal drugs in the form of sprays. These drugs can quickly penetrate the skin surface and kill bacteria and other microorganisms.

Disinfectants and Anti-inflammatory

At CD Formulation, we can make anti-inflammatory drugs or immunomodulatory drugs into topical sprays or nasal sprays, which can be applied to the diseased area to effectively relieve symptoms and shorten the course of the disease.

Advantages of Our Veterinary Spray Development Services

With tools such as high-speed imaging, laser diffraction, and spectroscopic techniques, we can precisely evaluate spray properties, enabling us to optimize formulation and ensure product quality.
We offer comprehensive expertise spanning product concept through commercialization, saving both time and costs versus developing in-house.
Optimized absorption and targeted delivery of veterinary active ingredients.
Precise control dosing regimens, and animal-friendly administration.

At CD Formulation, we are committed to providing comprehensive veterinary spray development services to meet the unique needs of the veterinary industry. Our expertise encompasses all aspects of veterinary spray formulation, from initial concept to final product. Contact us today to explore the possibilities of our veterinary spray development services!

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