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Transdermal Formulation Tack Testing

Inquiry

A transdermal patch is a drug patch that can be directly attached to the skin. Its drug ingredients can be absorbed through the skin and enter the body to achieve the purpose of treating diseases. Since transdermal patches require direct contact with the skin, their tack is very important for drug absorption and therapeutic effectiveness. CD Formulation can provide you with professional transdermal formulation tack testing.

About Transdermal Formulation Tack Testing

The tack reflects the ability of the patch and patch paste to resist deformation or breakage caused by persistent external force. If the adhesiveness of the patch is insufficient, it may cause the drug to fall off prematurely on the skin, thereby affecting drug penetration and absorption and reducing the therapeutic effect. A patch with good adhesion can adhere firmly to the skin and is not easy to fall off, ensuring a good user experience for patients.

What Can We Offer

Product quality control

Through tack testing, we can ensure that the viscosity of each batch of patches meets the specified technical requirements and product specifications, avoiding usage problems caused by insufficient or excessive viscosity.

Performance optimization

Through tack testing, we can help you optimize the formulation and process of the patch to achieve the best user experience and effect.

Product development

We can help you evaluate the effects of different formulations and structural designs. Compare the performance of different samples in terms of adhesion and peeling force to select the best formulation or design.

User experience

Through tack testing, we can ensure that the patch can adhere firmly to the skin surface during use and can be easily peeled off when needed.

Our Workflow of Transdermal Formulation Tack Testing

The following is our process for using a tensile testing machine to test patch tack:

Workflow of transdermal formulation tack testing. Fig.1 Flow chart of transdermal formulation tack testing (CD Formulation)

Our Technology Platform

We commonly use the following methods to evaluate patch adhesion:

Technology Description
Inclined plate method Paste the patch sample on an inclined steel plate, and adjust the tilt angle to observe the time or distance the patch slides off to evaluate its tack.
Rolling ball method Roll a ball of a certain mass on an inclined surface with a fixed angle, and observe the time or distance the ball sticks when it comes into contact with the patch during rolling to evaluate the tack of the patch.
Tensile test method Using a tensile testing machine, secure one end of the patch to the testing machine and apply a pulling force to the other end until the patch falls off the test surface. Tack is assessed by measuring the amount and duration of pull required.

Why Choose Us for Transdermal Formulation Tack Testing?

  • We are equipped with professional adhesion testing equipment and technology to accurately and reliably evaluate the tack performance of patches under different conditions.
  • We have extensive testing experience and expertise to efficiently conduct tack testing and provide timely test reports and analysis results.

Published Data

Technology: Methods to transdermal formulation tack testing

Journal: Chinese Pharmaceutical Affairs

IF: 1.16

Published: 2023

Results: The study reviewed the characteristics of dosage forms and technological advancements in transdermal patches. It systematically summarized the quality control indicators for transdermal patches. The evaluation included key quality indexes such as drug release, transdermal properties, tack, peel adhesion, and drug residue.

Transdermal patch tack testing is of great significance for evaluating the stability and reliability of transdermal patches and promoting the improvement and development of transdermal patch technology. If you have any needs, please feel free to contact us and our colleagues will reply to you within three working days.

References

  1. Huang Ting, Zhang Jing, et al. Research Progress in Technology and Quality Control of Transdermal Patches. Chinese Pharmaceutical Affairs. 2023, Volume 37, issue 9.
How It Works
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Execute the project with real-time communication, and deliver the final report promptly.
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