Transdermal Formulation Swelling Index Testing

The swelling index of a transdermal patch measures its capacity to absorb water and swell upon contact with skin or other biological surfaces. This is essential for designing and evaluating the performance of transdermal patches. CD Formulation offers professional testing services for transdermal formulation swelling index.

About Transdermal Formulation Swelling Index Testing

The patch may hydrate and swell when in contact with the skin, affecting its adaptability to the skin and the release rate and transdermal delivery efficiency of the drug. The Swelling Index testing can evaluate the degree of hydration and swelling of a patch when it comes into contact with the skin, helping to determine its irritation and adaptability to the skin, understanding the impact of the hydration layer formed by the patch on the skin surface on drug release will provide a reference for the pharmacodynamic evaluation of the patch.

Our Workflow of Transdermal Formulation Swelling Index Testing

The hydration-swelling properties of the patch can help guide product design and optimization. Based on the swelling index testing results, we can adjust the ingredient ratio, material selection and preparation process of the patch for you to improve the performance and adaptability of the patch.

Our steps for transdermal formulation swelling index testing are as follows:

Fig.1 Flow chart of transdermal formulation swelling index testing (CD Formulation)

Why Choose Us for Transdermal Formulation Swelling Index Testing?

Our testing staff are experienced, and our laboratory is equipped with all required testing instruments:

• Digital calipers or microscope: Used to measure dimensional changes in patch samples before and after they are soaked in solution. Digital calipers can be used to measure the length, width, and thickness of the patch, while a microscope can be used to observe small dimensional changes or changes in surface structure.
• Weigher: Used to accurately weigh the mass of a patch sample to accurately determine the initial size when calculating the swelling index.
• Thermostatic bath or thermostat box: used to control the temperature of the solution to ensure that the test is conducted under stable temperature conditions. Baths are typically used for smaller sample volumes, while incubators are suitable for larger sample volumes.

Published Data

The swelling index testing of a patch helps evaluate its hydration swelling performance when in contact with the skin, providing important information for the design, optimization and quality control of the patch. If you have any needs, please feel free to contact us and our colleagues will reply to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.