Transdermal Formulation Shear Testing

Shear testing can accurately assess the stability and performance of a patch when subjected to shear forces. This is critical for understanding the adhesion and persistence of the patch in real-world applications, helping with product design, manufacturing, and use. CD Formulation offers professional transdermal formulation shear testing services.

About Transdermal Formulation Shear Testing

The shear test of the transdermal patch mainly measures the maximum stress value that the interface of the patch can withstand when it is subjected to shear force. This shear force generally refers to the force exerted along the direction of the interface between the patch and the object to which it is adhered and is used to evaluate the adhesive performance and stability of the patch when subjected to such forces. The results of the shear test are usually expressed in terms of shear strength. The larger the value, the better the adhesive performance and stability of the patch.

What Can We Offer

• Based on the shear force test results, we can optimize the material formulation of the patch to improve its adhesion and stability. For example, we can adjust the type and amount of adhesive or add tackifiers.
• We can also help optimize the structural design of the patch, such as changing the shape, size or backing material of the patch to improve its fit and ease of use.
• Through shear testing, we can ensure that the patch will not fall off or break when subjected to external forces, thereby avoiding drug leakage and inaccurate dosage.

Our Workflow of Transdermal Formulation Shear Testing

The following is our process for shear testing:

Fig.1 Flow chart of transdermal formulation shear testing (CD Formulation)

1. Prepare the sample: Apply the patch evenly to the chosen substrate, making sure the surface is clean and flat, and wait for the patch to dry completely. Samples are cut into standard sizes, usually strips or squares, for testing.

2. Securing the sample : One end is secured to the test equipment, usually by clamping the substrate in a clamp, ensuring that the sample is stable.

3. Applying shear force: Shear force is applied through the test equipment, usually at a certain speed or with a certain force to shear the patch. This can be unidirectional shear or reciprocating shear, depending on the specific test requirements.

4. Duration: The duration of the patch under applied shear force is recorded and is usually tested over a set period of time to assess its long-lasting performance.

5. Data analysis: According to the output data of the testing equipment, the changes in shear force and time during the shearing process can be analyzed to obtain the relationship curve between shear stress and time.

Our Technology Platform

We commonly use the following methods to evaluate patch shear:

Why Choose Us for Transdermal Formulation Shear Testing?

• We are equipped with professional equipment to evaluate the stability of the patch when subjected to shear forces.
• Our experienced technicians can evaluate the level of adhesion through shear force testing.

Shear testing is one of the important aspects of transdermal patch quality control. By testing shear stress on patches from different batches and production lines, we can ensure product consistency and stability and avoid quality issues. If you have any needs, please feel free to contact us and our colleagues will reply to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.