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Transdermal Formulation Residual Drug Analysis

Inquiry

A transdermal patch is a drug delivery system that delivers drugs through the skin. It can deliver drugs into the body continuously and stably. After using a transdermal patch, sometimes some of the medicine may remain on the patch or on the skin. CD Formulation can provide you with professional transdermal formulation residual drug analysis.

About Transdermal Formulation Residual Drug Analysis

In order to maintain a relatively stable drug release rate, the drug content in the transdermal patch is usually higher than the delivered dose during use to achieve a clinically effective delivery rate. Since the concentration of the active ingredient may be close to its saturation limit, a large amount of drug will remain in the patch after the product is used, and there is also a risk of drug crystallization during product storage. Excessive residual drugs in patch products increase the possibility of drug abuse.

What Can We Offer

  • Through residual drug analysis of patches, we can help you ensure the accuracy of drug dosage.
  • Through residual drug analysis of patches, we can help you evaluate drug absorption.
  • Through residual drug analysis of patches, we can monitor drug abuse and drug resistance.
  • Through residual drug analysis of patches, we can understand the metabolism of drugs in the body.
  • Through residual drug analysis of patches, we can understand the degree of drug pollution to the environment.

Our Workflow of Transdermal Formulation Residual Drug Analysis

At CD Formulation, our testing process is generally as follows:

Workflow for the analysis of residual drugs in transdermal formulations. Fig.1 Flow chart of residual drug analysis (CD Formulation)

Our Technology Platform

We have professional testing equipment to provide you with transdermal formulation residual drug analysis services.

Instrument Description
Chromatography Such as high-performance liquid chromatography (HPLC), gas chromatography (GC), etc., which can be used for quantitative and qualitative analysis of drug residues.
Mass Spectrometry Combined with chromatography (such as LC-MS, GC-MS) to provide higher sensitivity and specificity.
Spectroscopy Such as ultraviolet-visible spectroscopy (UV-Vis), infrared spectroscopy (IR), etc., which can be used for structural identification and quantitative analysis of drugs.

Why Choose Us for Analyzing Residual Drug Transdermal Formulations?

  • We have professional testing equipment and technical personnel. After we analyze the residual drug in the patch, we can evaluate the release and bioavailability of the drug in the patch, helping you optimize the design and production process of pharmaceutical formulations.
  • Our technical staff have extensive experience and knowledge in drug testing. Through drug residue analysis, we can evaluate the drug concentration and residual amount on the skin surface after the use of transdermal patches, predict possible side effects, and promptly detect and deal with possible skin irritation, allergic reactions and other adverse reactions.

Published Data

Technology: Methods to transdermal formulation residual drug analysis

Journal: Chinese Pharmaceutical Affairs

IF: 1.16

Published: 2023

Results: In the study, the characteristics and technological advancements of transdermal patches' dosage forms were reviewed. The research also systematically summarized the quality control indicators of transdermal patches. Key quality indexes such as drug release, transdermal properties, adhesion, cold flow, and drug residue of transdermal patches were thoroughly evaluated.

Transdermal patch drug residue analysis has significant advantages in drug utilization assessment, side effect assessment, and drug development. CD Formulation can provide you with professional transdermal formulation residual drug analysis. If you have any needs, please feel free to contact us and our colleagues will reply to you within three working days.

References

  1. Huang Ting, Zhang Jing, et al. Research Progress in Technology and Quality Control of Transdermal Patches. Chinese Pharmaceutical Affairs. 2023, Volume 37, issue 9.
How It Works
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STEP 3
Execute the project with real-time communication, and deliver the final report promptly.
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