Transdermal Formulation Drug Content Uniformity Testing

Content uniformity refers to the extent to which the content of small-dose solid preparations, semi-solid preparations and heterogeneous liquid tablets conforms to the labeled amount. During the pharmaceutical production process, certain small-dose dosage forms are prepared by advanced processes, which may cause differences in content uniformity. CD Formulation is equipped with a variety of testing instruments to provide professional testing services for the content uniformity of your transdermal formulation.

About Transdermal Formulation Drug Content Uniformity Testing

The content uniformity of the transdermal formulation is not good, that is, there are significant differences in the drug content in different parts. Then when used, the release and absorption of the drug on the skin will also be uneven, which may lead to inconsistent or reduced therapeutic effects. Therefore, the drug content uniformity test of transdermal formulation is to ensure that the distribution of the drug in the preparation is uniform, thereby ensuring the accuracy of the drug dosage and the consistency of the therapeutic effect.

How to Test Transdermal Formulation Drug Content Uniformity?

At CD Formulation, the commonly used method flow is as follows:

Fig.1 Flow chart of drug content uniformity testing (CD Formulation)

Our Capabilities for Testing Transdermal Formulation Drug Content Uniformity

Our transdermal formulation drug content uniformity testing methods include but are not limited to the following:

Highlights of Our Transdermal Formulation Drug Content Uniformity Testing

We have a variety of equipment to meet your testing needs:

• High performance liquid chromatography (HPLC): HPLC is suitable for analyzing the content uniformity of drugs in transdermal formulation. It can accurately measure the concentration of drugs with high sensitivity and accuracy.
• Mass spectrometer (MS): Mass spectrometer combines the principles of mass analysis and analytical chemistry and can be used to identify and quantify drug ingredients in transdermal formulation. Mass spectrometry is particularly useful for components that are present in relatively low amounts and for components that are structurally specific.

• Scanning electron microscope (SEM): SEM can be used to observe the surface morphology and microstructure of transdermal formulation and evaluate the distribution of drugs in the patches. It provides visual observation of drug content uniformity.

Published Data

CD Formulation provides drug content uniformity testing based on the United States Pharmacopeia (USP) and European Pharmacopeia (EP) standards, in compliance with relevant regulations and requirements to ensure the accuracy and reliability of test results. Contact us to learn more about how we can work for you, and our colleagues will reply to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.