Transdermal Formulation Drug Content and Excipient Content Assays

The detection of drug content and excipient content of transdermal formulation is one of the quality control steps in the production process of transdermal formulation. CD Formulation has rich project experience in the testing of drug content and excipients in transdermal drug delivery formulation.

About Transdermal Formulation Drug Content and Excipient Content Assays

The drug content of transdermal formulation refers to the amount of principal components contained in the drug, which is an important index to evaluate the quality of the drug.

Medicinal excipients refer to all medicinal materials except the main drug that are added to the prescription to solve the formability, effectiveness, stability, and safety of the formulation when designing the prescription. The selection and concentration of excipients may affect the properties of the drug.

What Can We Offer

Our transdermal formulation drug content and excipient content assays mainly have the following applications:

Optimize process

By testing the content of drug and excipient in different batches of transdermal formulation, changes in the production process can be understood and the production process can be optimized.

Quality control

Through testing, it can be ensured that the content of active ingredients and excipient in transdermal formulation meets standards and specifications.

Support R&D work

Content testing of drug and excipient can help R&D personnel understand the composition and properties of the product, thereby optimizing the formula and improving the preparation process.

Our Workflow of Transdermal Formulation Drug Content and Excipient Content Assays

Fig.1 Flow chart of drug content and excipient content assays (CD Formulation)

1. Sample preparation

For transdermal formulation, the determination of the content needs to be processed in a specific way for subsequent analysis. The patch was cut up and the main drug was extracted with a suitable solvent. The selection of solvent, extraction time and interference of isolation layer/backing layer would affect the accuracy of content determination.

2. Setting chromatographic conditions

The column selection, mobile phase combination, flow rate, column temperature and other conditions need to be determined according to the nature of the drug, the interference of the excipients and the sensitivity of the method.

3. Instrument analysis

The prepared sample is injected into the analytical instrument to detect the content of drugs and excipients.

4. Result processing and reporting

Multiple measurements and averaging, or methodological validation, are required. The final results are presented in the form of a report, including sample information, assay methods, assay results, etc.

Our Platform for Transdermal Formulation Drug Content and Excipient Content Assays

• High performance Liquid Chromatograph (HPLC)
• Gas Chromatograph (GC)
• Ultraviolet spectrophotometer
• Infrared spectrometer
• Mass spectrometer

Highlights of Our Transdermal Formulation Drug Content and Excipient Content Assays

• Short cycle: Professional raw materials testing team, provide professional advice, high efficiency, short testing cycle.
• Low cost: Complete industry chain, with its own laboratory, reduce costs from the source.
• Attentive service: 7*24 hours service, to provide you with pre-sales and after-sales service.
• Advanced equipment: Advanced testing equipment, a variety of testing means to ensure the detection accuracy.
• Accurate data: The detection and analysis accuracy is close to 100% to ensure accurate data.

Published Data

CD Formulation provides content testing of drugs and raw materials and excipients based on United States Pharmacopeia (USP) and European Pharmacopoeia (EP) standards. Contact us to learn more about how we can work for you, and our colleagues will reply to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.