Transdermal Formulation Appearance Analysis

CD Formulation provides physical parameter testing services for transdermal formulations, as well as conventional characterization of transdermal formulations, etc., which can reflect the actual situation of transdermal formulations. By understanding these parameters of transdermal formulations, we can better develop transdermal formulations. Here, we provide common transdermal formulation appearance analysis services.

About Transdermal Formulation Appearance Analysis

Transdermal formulations generally consist of several layers, including a backing layer, a drug-containing matrix, pressure-sensitive adhesive, and a protective layer. Usually, the appearance of a transdermal formulation can tell whether there are obvious quality defects in the product. The appearance of the transdermal formulations should be complete and smooth, with a uniform application area, and the cutouts should be smooth and without sharp edges.

What Can We Offer

Our appearance analysis includes the following aspects:

Fig.1 Types of transdermal patches: (A) drug-in adhesive system; (B) Reservoir system; (C) matrix Figure 2. Types of transdermal patch (Won Fen Wong, et al., 2023)

Overall Observation

Check the overall shape and size of the patch to ensure that it meets the specifications. Observe whether the color of the patch is uniform and consistent, without obvious color differences or color changes.

Surface Quality

Check whether the surface of the patch is flat and smooth, without defects such as bubbles, wrinkles, unevenness or stains. Use a magnifying glass to carefully observe the surface for tiny foreign objects, particles or scratches.

Edge Inspection

Check whether the edges of the patch are neat, without damage or burrs. Ensure that the adhesive part of the edge does not lift or separate.

Printing and Labeling

If there is printing or labeling on the patch, check whether it is clear and complete, without blurring, falling off or misalignment. Check the information on the printing or label to ensure it is accurate.

Dimension Measurement

Use measuring tools such as calipers and gauges to accurately measure the size of the patch to ensure that it meets the specifications.

Transparency/Gloss

For transparent or translucent patches, check whether their transparency is consistent and whether there are no turbidity or color spots. For patches with gloss requirements, check whether the gloss meets the standard and whether there is dullness or uneven gloss.

Our Capabilities for Appearance Analysis of Transdermal Formulation

We have various instruments and equipment for analysis inspection of transdermal formulation to ensure product quality and compliance with standards.

• Microscope: used to observe the surface and texture of transdermal formulation to check for the presence of foreign matter, bubbles, cracks and other defects.
• Colorimeter: used to measure the color of transdermal formulation to ensure that the color meets the specified standard range.
• Specular reflectometer: used to check the flatness and gloss of the transdermal formulation surface.

Our Workflow of Analyzing Transdermal Formulation Appearance

Our appearance analysis checks all aspects of transdermal formulations such as color, size, shape, etc. The process is as follows:

Fig.2 Flow chart of transdermal formulation appearance analysis (CD Formulation)

Advantages of Our Transdermal Formulation Appearance Analysis Services

• Our appearance inspection will not cause damage to the product and can be performed multiple times.
• Our appearance inspection can be completed in a short time and can improve production efficiency.
• Our appearance inspection can comprehensively inspect all aspects of the product, including surface flatness, color consistency, size, etc., to ensure product compliance.

Published Data

CD Formulation has served more than a hundred pharmaceutical companies, formulating systematic solutions based on customers' real needs, aiming to provide customers with high-quality overall solutions. If you have any needs, please contact us in time.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.