CD Formulation provides advanced solutions for transdermal dissolving microneedle patch development, designed to offer a painless, efficient, and controlled drug delivery system. This technology is ideal for researchers seeking effective alternatives to traditional methods like injections.
Dissolving microneedles is the preparation of biodegradable polymer materials and drugs into microneedles. After being penetrated by the skin, the microneedles composed of biodegradable materials gradually degrade in the microenvironment, drug molecules are released simultaneously, and drug molecules are absorbed into the human body through the cuticle barrier and subcutaneous tissue. Dissolving microneedle drug delivery eliminates the need to form micropores to deliver drugs and remove the needle body as with other microneedles, greatly improving patient compliance, while not reusing microneedles also reduces the risk of cross-infection.
Fig.1 (A) Schematic diagram of different microneedles applied to (a) skin and (b) drug delivery. (B) Relevant content of dissolution microneedles. (Xueqing, et al. 2023)
Dissolving microneedles stand out in the industry due to their unique benefits:
Dissolving microneedles represent a versatile and advanced technology with numerous applications in the medical and cosmetic fields.
Drug Delivery | Cosmetic and Dermatological Applications | Diagnostic Applications |
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Vaccination | Anti-Aging Treatments | Biosensing and Monitoring |
Peptide Delivery | Skin Brightening |
CD Formulation focuses on the use of advanced biocompatible materials. Our team selects polymers and biodegradable substances that dissolve safely within the skin, enabling precise medication release at the required rate.
The matrix material of dissolving microneedles should meet the following requirements:
Fig.2 The requirements for the matrix material of dissolving microneedles. (CD Formulation)
Key matrix materials include:
Materials | Details |
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Polymer Materials |
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Microsphere Materials |
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The preparation of dissolving microneedles involves several advanced technologies and techniques to ensure their effectiveness and functionality. The following is our commonly used microneedle preparation method:
Technology: Technology for Dissolving Microneedle Patch
Journal: Polymers
IF: 4.7
Published: 2023
Results: In recent years, microneedle technology has been widely used for the transdermal delivery of substances, showing improvements in drug delivery effects with the advantages of minimally invasive, painless, and convenient operation. With the development of nano- and electrochemical technology, different types of microneedles are increasingly being used in other biomedical fields. Recent research progress shows that dissolving microneedles has achieved remarkable results in the fields of dermatological treatment, disease diagnosis and monitoring, and vaccine delivery, and they have a wide range of application prospects in various biomedical fields, showing their great potential as a form of clinical treatment.
Dissolving microneedles represent a cutting-edge approach to enhancing drug delivery. Offering a painless and controlled method of administration, this technology is highly advantageous for numerous biomedical applications. For specialized development of dissolving microneedle patches, please do not hesitate to contact us. As a contract research and development biotechnology company, we provide tailored transdermal technology R&D services to researchers. Our team will get back to you within three working days.
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