Here's how you can reach us...
  • Tel:
  • Email:

Transdermal Dissolving Microneedle Patch Development

Inquiry

CD Formulation provides advanced solutions for transdermal dissolving microneedle patch development, designed to offer a painless, efficient, and controlled drug delivery system. This technology is ideal for researchers seeking effective alternatives to traditional methods like injections.

About Transdermal Dissolving Microneedle Patches

Dissolving microneedles is the preparation of biodegradable polymer materials and drugs into microneedles. After being penetrated by the skin, the microneedles composed of biodegradable materials gradually degrade in the microenvironment, drug molecules are released simultaneously, and drug molecules are absorbed into the human body through the cuticle barrier and subcutaneous tissue. Dissolving microneedle drug delivery eliminates the need to form micropores to deliver drugs and remove the needle body as with other microneedles, greatly improving patient compliance, while not reusing microneedles also reduces the risk of cross-infection.

Fig.1 Illustration of different microneedles applied to skin and their drug delivery mechanisms.Fig.1 (A) Schematic diagram of different microneedles applied to (a) skin and (b) drug delivery. (B) Relevant content of dissolution microneedles. (Xueqing, et al. 2023)

Advantages of Transdermal Dissolving Microneedle Patches

Dissolving microneedles stand out in the industry due to their unique benefits:

  • Biodegradable and cost-effective: Utilize environmentally friendly, low-cost materials.
  • High biocompatibility: Suitable for a wide range of drugs, with a high safety profile.
  • Efficient dissolution: Dissolve after skin penetration for seamless drug delivery.
  • Scalable technology: Growing market demand supports wide-ranging applications.

Applications of Transdermal Dissolving Microneedle Patches

Dissolving microneedles represent a versatile and advanced technology with numerous applications in the medical and cosmetic fields.

Drug Delivery Cosmetic and Dermatological Applications Diagnostic Applications
Vaccination Anti-Aging Treatments Biosensing and Monitoring
Peptide Delivery Skin Brightening

Customized Development of Transdermal Dissolving Microneedle Patches

Material Innovation

CD Formulation focuses on the use of advanced biocompatible materials. Our team selects polymers and biodegradable substances that dissolve safely within the skin, enabling precise medication release at the required rate.

The matrix material of dissolving microneedles should meet the following requirements:

Fig.2 Chart showing material requirements for dissolving microneedles, including biocompatible polymers.Fig.2 The requirements for the matrix material of dissolving microneedles. (CD Formulation)

Key matrix materials include:

Materials Details
Polymer Materials
  • Polyvinyl alcohol (PVA)
  • Polyvinylpyrrolidone (PVP)
  • Hyaluronic acid (HA)
  • Dextran (Dex)
  • Chitosan (Cs)
  • Sodium alginate (Sa)
Microsphere Materials
  • Polylactic acid (PLA)
  • Polylactic-co-glycolic acid (PLGA)

Our Microneedle Manufacturing Method

The preparation of dissolving microneedles involves several advanced technologies and techniques to ensure their effectiveness and functionality. The following is our commonly used microneedle preparation method:

  • Micromolding Techniques: Micromolding is one of the most common methods for creating and dissolving microneedles. It involves creating a mold with the desired microneedle shape and then using this mold to form the microneedles.
  • 3D Printing: It enables precise, customizable designs for specific drug delivery research needs.
  • Casting and Injection Molding: This method involves casting a polymer solution into a mold to form microneedles.

Why Choose CD Formulation?

  • Innovative Microneedle Design: We provide custom designs that optimize comfort and drug delivery.
  • Material Expertise: We use cutting-edge, biocompatible materials for safe and efficient results.
  • Tailored Solutions: We customize microneedle patches for specific research requirements, offering varied dosages and controlled delivery rates.

Published Data

Technology: Technology for Dissolving Microneedle Patch

Journal: Polymers

IF: 4.7

Published: 2023

Results: In recent years, microneedle technology has been widely used for the transdermal delivery of substances, showing improvements in drug delivery effects with the advantages of minimally invasive, painless, and convenient operation. With the development of nano- and electrochemical technology, different types of microneedles are increasingly being used in other biomedical fields. Recent research progress shows that dissolving microneedles has achieved remarkable results in the fields of dermatological treatment, disease diagnosis and monitoring, and vaccine delivery, and they have a wide range of application prospects in various biomedical fields, showing their great potential as a form of clinical treatment.

Dissolving microneedles represent a cutting-edge approach to enhancing drug delivery. Offering a painless and controlled method of administration, this technology is highly advantageous for numerous biomedical applications. For specialized development of dissolving microneedle patches, please do not hesitate to contact us. As a contract research and development biotechnology company, we provide tailored transdermal technology R&D services to researchers. Our team will get back to you within three working days.

References

  1. Xueqing Yu, Jing Zhao, et al. The Progress in the Application of Dissolving Microneedles in Biomedicine. Polymers. 2023, 15(20), 4059.
How It Works
STEP 2
We'll email you to provide your quote and confirm order details if applicable.
STEP 3
Execute the project with real-time communication, and deliver the final report promptly.
Related Services
Inquiry

CD Formulation is a global force in transdermal delivery and manufacturing. We provide a wide range of contract development and manufacturing services that are specifically designed to cater to...

Learn More

  • Tel:
  • Email:

Stay up to date with our latest releases of new research and promotions.

Copyright © CD Formulation. All Rights Reserved.