Solid Lipid Nano Transdermal Patches are an innovative approach to drug delivery that combines the benefits of solid lipid nanoparticles (SLNs) with the convenience of transdermal patches. This technology enhances the delivery, stability, and effectiveness of active pharmaceutical ingredients (APIs) through the skin, offering a versatile solution for various therapeutic and cosmetic applications. CD Formulation can provide you with professional solid lipid nano transdermal patch development service.

About Solid Lipid Nano Transdermal Patches

Solid lipid nano transdermal patches use solid lipid nanoparticles (SLNs) to deliver APIs through the skin. SLNs are solid lipid-based particles typically ranging from 50 to 1000 nanometers in size, consisting of a solid lipid core encased in a surfactant layer, which helps stabilize the particles and facilitate their penetration through the skin. APIs are encapsulated within the solid lipid core of the nanoparticles, protecting them from degradation and enhancing their stability. SLNs provide a controlled and sustained release of APIs, improving therapeutic efficacy and reducing the need for frequent application.

Fig.1 The chemical protection of the merged constituents, permitting the dermal use of labile particles that are problematic to conveyance in classical semi-solid preparations; enhanced medication bioavailability, linked to the opportunity of modifying particle release, endorsing their dermal permeation and retaining. (Saud Almawash, 2023)

Advantages of Solid Lipid Nano Transdermal Patches

Solid lipid nano transdermal patches offer benefits such as enhanced skin hydration, UV protection, and improved delivery of encapsulated drugs.

Fig.2 The Advantages of Solid Lipid Nano Transdermal Patch. (CD Formulation)

Our Solid Lipid Nano Transdermal Patch Development Services

Formulation and Design

• Lipid Selection: Selecting solid lipids for optimal drug release and stability.
• Encapsulation Efficiency: Ensuring high efficiency in encapsulating APIs within the solid lipid nanoparticles to maximize drug delivery.

Manufacturing Process

• Nanoparticle Preparation: Utilizing techniques like high-pressure homogenization, melt-emulsification, and solvent evaporation to produce stable SLNs.
• Patch Integration: Incorporating SLNs into patches that ensure compatibility, adhesion, and comfort.

Testing and Quality Control

• Performance Testing: Conducting in vitro and in vivo studies for drug delivery efficacy, skin penetration, and desired outcomes.
• Stability Testing: Evaluating the stability of SLNs and the overall patch to ensure consistent performance over time.

Methods of SLN Preparation

SLN is composed of solid lipids, emulsifiers and water/solvent. Our commonly used SLN preparation methods are as follows:

• High shear homogenization
• Hot and cold homogenization
• Ultrasonication/high-speed homogenization
• Solvent emulsification/evaporation
• Spray drying
• Double emulsion technique
• Bath ultrasonication

Why Choose CD Formulation?

• Expert Team: Our team of specialists has extensive experience in nanotechnology and transdermal systems, providing cutting-edge drug delivery solutions.
• Advanced Facilities: Equipped with state-of-the-art technology for nanoparticle synthesis, formulation, and quality testing, we ensure high standards in every project.
• Quality Assurance: We implement strict quality control measures, focusing on stability, efficacy, and safety to deliver reliable transdermal patch solutions.

Published Data

By choosing us, you gain a partner with deep expertise, advanced technology, and a commitment to delivering high-quality solid lipid nano transdermal patches. We are dedicated to driving your project's success through innovative solutions, rigorous quality control, and a collaborative approach. If you have any needs, please do not hesitate to contact us, and our colleagues will contact you within three working days.