Peptide Transdermal Formulation Development

In recent years, peptide transdermal formulations have become a hot topic in skincare and medicine. Through specific technologies and formulas, these formulations enable bioactive ingredients such as peptides to penetrate the skin barrier and enter the deep layers of the skin, thereby exerting their anti-aging, absorption promotion, repair, and other effects. CD Formulation has professional knowledge and technology accumulation in peptide transdermal formulation development and can provide several peptide transdermal formulation development services.

About Peptide Transdermal Formulations

Fig.1 Schematic representation of routes for topical delivery of cell-penetrating peptides (CPP)/Cargo complexes through human skin. (Saman A. Nasrollahi, et al. 2012)

Peptide transdermal formulations refer to formulations that contain peptide ingredients and use specific technologies (such as carrier technology, penetration enhancers, modification technology, etc.) to improve the transdermal absorption capacity of peptide ingredients. With the development of life sciences, more and more protein peptide drugs are used in clinical practice, but such drugs are easily hydrolyzed by oral administration and other methods. Compared with other mucous membranes, the skin contains fewer proteolytic enzymes, which is conducive to the stability of peptide drugs. In addition, transdermal administration can maintain a constant optimal blood drug concentration or physiological effect, prolong the effective action time, and reduce the number of administrations. By changing the administration area to adjust the dosage, patients can also take the drug independently and stop taking the drug at any time.

Key Characteristics of Peptide Transdermal Formulations

Peptide transdermal formulations exhibit unique clinical advantages, including improved stability, prolonged action time, and reduced administration frequency.

Fig.2 Characteristics of Peptide Transdermal Formulation (CD Formulation)

What Can We Offer?

Advanced Genetic Engineering Technology

We have first-class genetic engineering technology research and development capabilities and can efficiently express and purify highly active peptide ingredients.

Auxiliary Ingredient Screening

We add auxiliary ingredients such as moisturizers, penetration enhancers, preservatives, etc. according to the requirements of the formulation to improve the stability and use effect.

Formula Optimization

We verify the interaction and compatibility between different ingredients through experiments, optimize the formula ratio, and ensure the stability and effectiveness of the formulation.

Workflow for Peptide Transdermal Formulation Development

1. Consultation: Understanding client's specific needs and requirements.
2. Research & Development: Employing genetic engineering and molecular biology techniques to create stable peptide formulations.
3. Formulation Optimization: Conducting rigorous testing and optimization to ensure efficacy, safety, and stability.
4. Quality Control: Implementing stringent quality checks and compliance with industry standards.
5. Delivery & Support: Providing comprehensive support and timely delivery to ensure client satisfaction.

Explore Our Technology Platforms

• Carrier technology: We use carrier technologies such as nanoparticles and liposomes to encapsulate peptide ingredients in carriers to improve their stability in the skin and transdermal absorption rate.
• Penetration-enhancing technology: We use ultrasound permeation, iontophoresis, microneedle, and other penetration-enhancing technologies to further improve the transdermal absorption efficiency of peptide ingredients.
• Modification technology: We chemically or biologically modify peptide ingredients to improve their lipophilicity or hydrophilicity, improving their transdermal absorption capacity.

Why Choose CD Formulation?

• We have made important breakthroughs in transdermal technology. To significantly improve the stability and transdermal efficiency of peptide components, use transdermal peptides to improve the transdermal absorption rate of peptide components and use new carrier technologies such as liposome encapsulation and technology.
• We not only focus on the development of single peptide ingredients but are also committed to compounding multiple peptide ingredients with other active ingredients to develop peptide transdermal formulations with multiple functions to meet the needs of different consumers.
• We have strong customized service capabilities and can provide personalized peptide transdermal preparation solutions according to the specific needs of customers to meet application needs in different scenarios.

Published Data

Peptide transdermal formulation can be used to treat many diseases, such as diabetes and neurodegenerative diseases. Through transdermal administration, the drug can directly act on the blood vessels and lymphatics under the skin, avoid the liver first pass effect, and improve the efficacy of the drug. CD Formulation has advanced technology, an excellent team abundant market resources, etc., which provide strong support for the development of peptide transdermal formulations. If you have any needs, please feel free to contact us, and our colleagues will contact you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.