Ointment Transdermal Formulation Development

Ointments are crucial in various medical fields such as dermatology, surgery, and gynecology. CD Formulation specializes in supporting the development of ointment transdermal formulations, providing comprehensive services from drug screening and formulation design to process development and performance testing.

Fig.1 Topical drug delivery systems. (Kashmira Kathe, et al. 2017)

About Ointment Transdermal Formulations

Ointments are semi-solid topical formulations that combine raw materials with oily or water-soluble bases. Their unique characteristics—soft texture, ease of application, and protective film formation—enable sustained drug release at the targeted site, enhancing therapeutic efficacy. The development of ointments is critical for drug effectiveness and patient acceptance. They can be categorized into solution, suspension, and emulsion types, with emulsion ointments also known as creams.

Key Features of Ointment Transdermal Formulations

• Pharmaceutical Applications: Ointments provide long-lasting adhesion, lubrication, and protection to the skin, making them ideal for treating various skin conditions.
• Systemic Benefits: With excellent adhesion and spreadability, ointments are suitable for chronic skin lesions, wound healing, and early-stage infectious diseases.
• Local Treatment: Ointments treat localized conditions such as infections, itching, pain, and can have systemic effects when absorbed through the skin.
• Usage Precautions: Oil-based ointments should be avoided for wounds with exudate, seborrheic dermatitis, or acne. Water-soluble bases are preferred for moist or erosive wounds.

What Can We Offer?

CD Formulation's platform offers a full range of services—from drug screening to performance testing—designed to accelerate ointment product development and reduce costs.

• Innovative Ingredients: We develop new drug ingredients for enhanced efficacy, reduced side effects, or broader indications.
• Formulation Optimization: We refine the ratios of matrices, excipients, and active ingredients to improve physical properties, stability, and transdermal performance.

We provide formulation development services for various dispersion systems, including solution, suspension, and emulsion types (creams).

Fig.2 Classification of Ointment Transdermal Formulations (CD Formulation)

Innovative Technologies

Nanotechnology

Through nanotechnology, drug particles can be prepared into nanoscale size, thereby improving the permeability of drugs, improving the release behavior of drugs, and thus improving the efficacy and reducing side effects. For example, new carrier systems such as nanoliposomes and nano microspheres have been used in ointments.

Microencapsulation

This technology encapsulates drugs in tiny capsules and achieves sustained and controlled release of drugs by the release rate of capsules. This can not only improve the efficacy of drugs but also reduce the frequency of administration and the medication burden of patients.

Laser and Ultrasound Technologies

Laser technology can promote the transdermal absorption of drug ingredients in ointments, while ultrasound technology may be used to improve local blood circulation and drug distribution.

Why Choose CD Formulation?

• Expert Team: Our multidisciplinary team includes pharmaceutical chemists, formulation scientists, and dermatologists, offering a comprehensive range of services.
• Advanced Equipment: Equipped with cutting-edge technology to ensure precise and reliable data.
• Extensive Experience: We leverage our extensive experience to deliver efficient, professional development services.
• One-Stop Service: Streamline your R&D process with our integrated services, reducing time and costs.

The development of transdermal ointment formulations aims to deliver drugs through the skin to achieve local or systemic therapeutic effects. During the development process, key quality attributes such as stability, bioavailability, skin permeability, safety and efficacy of the formulations need to be focused on. We are committed to solving the technical barriers of transdermal drug delivery formulations and improving product quality and efficacy. If you have any needs, please feel free to contact us and our colleagues will contact you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.