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Nanofiber/Microfiber Transdermal Patch Development

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At CD Formulation, we specialize in cutting-edge nanofiber/microfiber transdermal patch development. Our solutions are the result of extensive research and collaboration, focusing on high-quality and efficient drug delivery systems. We leverage advanced materials and state-of-the-art electrospinning techniques to meet the needs of researchers seeking custom transdermal formulations.

About Nanofiber/Microfiber Transdermal Patches

In recent years, the nanotechnology approach has been recognized as a promising way to develop new products. Among the technologies used to realize materials at the nanoscale or to be able to manipulate substances at the nanoscale, electrospinning is one of the most promising and fastest growing. Electrospinning is widely recognized as a simple, cost-effective technology that is easy to scale from the laboratory to commercial production. The increased surface area of nanofibers compared to standard bandages gives them a unique ability to increase the release of therapeutic substances. By varying the processing parameters, electrospinning can produce fibers at the nanometer to micron scale, fibers with random or oriented orientation, and smooth or porous surface structures, allowing for control of the porosity and pore size of the film, both of which are important in transdermal patch applications.

Fig.1 Diagram showing components of a dual-layer PVA patch for drug delivery.Fig.1 Components of proposed DS-Medicated dual layer PVA patch. (Shafizah Sa`adon, et al. 2021)

Advantages of Nanofiber/Microfiber Transdermal Patches

Fig.2 Infographic illustrating the benefits of nanofiber/microfiber transdermal patches.Fig.2 The Advantages of Nanofiber/Microfiber Transdermal Patch. (CD Formulation)

Applications of Nanofiber/Microfiber Transdermal Patches

Applications Description
Medication Delivery Effective for various drugs, including analgesics, hormones, and vaccines, these patches can manage chronic conditions and ongoing therapies.
Vaccine Delivery Research suggests transdermal patches can streamline immunization, potentially enhancing vaccine distribution and uptake.
Cosmetic Applications Ideal for delivering active ingredients that improve skin health and appearance, offering an alternative to traditional cosmetic formulations.

Our Nanofiber/Microfiber Transdermal Patch Development Services

Formulation Design and Optimization

  • Active Ingredient Integration: Our services include formulating and incorporating active pharmaceutical ingredients (APIs) into the patch matrix to ensure stable and effective drug delivery.
  • Release Rate Optimization: Our team optimizes release mechanisms for controlled and sustained therapeutic effects, minimizing side effects.
  • Compatibility Testing: We conduct thorough tests to ensure that the chosen materials and formulations are compatible with each other and the skin.

Electrospinning Technique: Core to Nanofiber and Microfiber Production

We can offer an innovative technology - electrospinning. Electrospinning produces nanofibers and microfibers, which are fundamental components in various applications, including textiles, biomedical devices, and drug delivery systems. Electrospinning is a method for creating fine fibers from a polymer solution or melt using an electric field. It is renowned for its ability to produce fibers with diameters ranging from nanometers to micrometers, making it an ideal choice for applications requiring high surface area-to-volume ratios and fine structural details.

Why Choose CD Formulation?

  • Material Selection: Our team provides expert guidance on selecting optimal nanofiber and microfiber materials to achieve desired drug release profiles and skin compatibility.
  • Quality Control: Our manufacturing process adheres to stringent quality control standards, including rigorous testing for consistency, efficacy, and safety.
  • Custom Solutions: We provide flexible manufacturing solutions to accommodate custom sizes, shapes, and formulations based on client requirements.

Published Data

Technology: Technology for Nanofiber/Microfiber Transdermal Patch

Journal: Pharmaceutics

IF: 5.4

Published: 2021

Results: This study aimed to prepare the diclofenac sodium (DS)-medicated dual-layer PVA patch using a combination of electrospinning and cryoablation (freeze-thaw) methods to improve the physicochemical properties and drug compatibility and investigate the release of the DS-medicated dual layer PVA patch. Morphological observations using scanning electron microscopy (SEM) verified the polymer−polymer interaction between both layers transform infrared (FTIR) spectroscopy has demonstrated the compatibility of DS in PVA matrix up to 2% w/v of PVA volume.

We focus on enhancing research and development for more effective and convenient transdermal technologies. If you are a researcher interested in our custom nanofiber/microfiber transdermal patch development services, please do not hesitate to contact us. Our team will contact you within three working days to address your needs.

References

  1. Shafizah Sa`adon, Mohamed Nainar Mohamed Ansari, et al. Electrospun Nanofiber and Cryogel of Polyvinyl Alcohol Transdermal Patch Containing Diclofenac Sodium: Preparation, Characterization and In Vitro Release Studies. Pharmaceutics. 2021, 13, 1900.
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